N,N-Dimethyl-N'-p-tolylsulphamide

Base Information

• Chemical Name: N,N-Dimethyl-N'-p-tolylsulphamide
• CAS No.: 66840-71-9
• Molecular Formula: C9H14N2O2S
• Molecular Weight: 214.288
• European Community (EC) Number: 266-491-0
• UNII: IOS7W692N5
• DSSTox Substance ID: DTXSID00891450
• Nikkaji Number: J310.157F
• Wikidata: Q27156853
• ChEMBL ID: CHEMBL1458342
• Mol file: 66840-71-9.mol

Synonyms:66840-71-9;N,N-Dimethyl-N'-p-tolylsulphamide;DMST;1-(dimethylsulfamoylamino)-4-methylbenzene;N,N-Dimethyl-N'-tolylsulfonyldiamide;Sulfamide, N,N-dimethyl-N'-(4-methylphenyl)-;UNII-IOS7W692N5;N,N-dimethyl-N'-(4-methylphenyl)sulfamide;IOS7W692N5;CHEBI:83470;N,N-dimethyl-N'-(4-methylphenyl)sulfuric diamide;EINECS 266-491-0;DMST 100 microg/mL in Acetonitrile;tolylfluanid TP;Maybridge3_004003;dimethyl-n-p-tolylsulfamide;DMST (II);Cambridge id 6182799;MLS000067488;F1196-0085;SCHEMBL3467606;CHEMBL1458342;DTXSID00891450;N,N-dimethyl-N'-p-tolylsulfamide;N,N-dimethyl-N'-p-tolysulphamide;HMS1442F21;HMS2185F21;N.N-Dimethyl-N'-p-tolylsulphamide;4-DIMETHYLAMINOSULFOTOLUIDIDE;CCG-45644;N,N-Dimethyl-N/'-P-tolylsulphamide;STK036039;AKOS000646866;IDI1_015390;dimethyl[(4-methylphenyl)sulfamoyl]amine;NCGC00245332-01;SMR000125003;CS-0331417;FT-0706683;AP-124/10330009;SR-01000635398-1;W-111276;Q27156853;Z57744695;N,N-dimethyl-N inverted exclamation marka-p-tolylsulfamide

Chemical Property of N,N-Dimethyl-N'-p-tolylsulphamide

Chemical Property:

• Melting Point: 80 °C
• Boiling Point: 319.7°Cat760mmHg
• PKA: 7.67±0.50(Predicted)
• Flash Point: 147.1°C
• PSA: 57.79000
• Density: 1.26g/cm³
• LogP: 2.36710
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility.: Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slig
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 214.07759887
• Heavy Atom Count: 14
• Complexity: 261

Purity/Quality:

99% ^*data from raw suppliers

4-Dimethylaminosulfotoluidide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F,T,Xn
• Hazard Codes: F,T,Xn
• Statements: 11-23/24/25-39/23/24/25-36-20/21/22
• Safety Statements: 36/37-45-16

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)NS(=O)(=O)N(C)C
• Uses: 4-Dimethylaminosulfotoluidide is an intermediate in the synthesis of Tolylfluanide (T536730), a polyvalent sulfamide fungicide that is closely related to dichlofluanide.

Technology Process of N,N-Dimethyl-N'-p-tolylsulphamide

There total 2 articles about N,N-Dimethyl-N'-p-tolylsulphamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

p-toluidine (106-49-0,12221-03-3) + dimethylamino sulfonyl chloride (13360-57-1) → N,N-dimethyl-N'-(4-methylphenyl)-sulfamide (66840-71-9)

Guidance literature:

Reference yield:

→ N,N-dimethyl-N'-(4-methylphenyl)-sulfamide (66840-71-9)

Guidance literature:

p-Toluidin, Dimethylaminosulfochlorid, Na2SO3, NaOH;

Reference yield:

N,N-dimethyl-N'-(4-methylphenyl)-sulfamide (66840-71-9) + dichlorofluoromethanesulphenyl chloride (2712-93-8) → dichloro-N-[(dimethylamino)sulfonyl]fluoro-N-(p-tolyl)methanesulfenamide (731-27-1)

Guidance literature:

N,N-dimethyl-N'-(4-methylphenyl)-sulfamide; With sodium hydride; In tetrahydrofuran; at 0 - 10 ℃; Inert atmosphere;

dichlorofluoromethanesulphenyl chloride; In tetrahydrofuran; at 20 ℃; Reagent/catalyst; Temperature; Inert atmosphere;

upstream raw materials:

p-toluidine

dimethylamino sulfonyl chloride

Downstream raw materials:

dichloro-N-[(dimethylamino)sulfonyl]fluoro-N-(p-tolyl)methanesulfenamide

Refernces

• 1、 -. "Synthetic method of CF3-containing indoline and 1,2,3,4-tetrahydroisoquinoline". Paragraph 0027; 0029; 0030; 0031; 0042. . Retrieved 2019/01/14.