1-Naphthaleneethanol

Base Information

• Chemical Name: 1-Naphthaleneethanol
• CAS No.: 773-99-9
• Molecular Formula: C12H12O
• Molecular Weight: 172.227
• Hs Code.: 2906299090
• European Community (EC) Number: 212-260-4
• NSC Number: 28342
• DSSTox Substance ID: DTXSID00228020
• Nikkaji Number: J101E
• Wikidata: Q69754377
• Mol file: 773-99-9.mol

Synonyms:773-99-9;1-Naphthaleneethanol;2-(1-Naphthyl)ethanol;2-(naphthalen-1-yl)ethanol;1-(2-HYDROXYETHYL)NAPHTHALENE;Naphthalen-1-ethanol;2-naphthalen-1-ylethanol;1-naphthalene ethanol;MFCD00004050;2-(naphthalen-1-yl)ethan-1-ol;EINECS 212-260-4;1-napthaleneethanol;NSC28342;Naphthalene-1-ethanol;2-(1-naphthy)ethanol;2-(naphth-1-yl)ethanol;2-(1-Naphthalene)ethanol;2-naphthalen-1-yl-ethanol;1-Naphthaleneethanol, 95%;SCHEMBL27550;2-(1-naphthyl)-1-ethanol;2-(.alpha.-Naphthyl)ethanol;1-(2-hydroxy-ethyl)-naphthalene;DTXSID00228020;AC1462;NSC 28342;NSC-28342;AKOS009158187;AC-4486;CS-W017592;FS-1800;SY020508;FT-0600741;N0575;EN300-1637768;AQ-917/40233986;W-104318;Z397587504

Chemical Property of 1-Naphthaleneethanol

Chemical Property:

• Appearance/Colour: off-white powder
• Melting Point: 62-65 °C
• Refractive Index: 1.5340 (estimate)
• Boiling Point: 311 °C at 760 mmHg
• PKA: 14.63±0.10(Predicted)
• Flash Point: 150.6 °C
• PSA: 20.23000
• Density: 1.119 g/cm³
• LogP: 2.37460
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: Chloroform (Slightly), Methanol (Slightly)
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 172.088815002
• Heavy Atom Count: 13
• Complexity: 155

Purity/Quality:

99% ^*data from raw suppliers

2-(1-Naphthyl)ethanol ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C=CC=C2CCO
• Uses: 2-(1-Naphthyl)ethanol is a toxic naphthalene derivative.

Technology Process of 1-Naphthaleneethanol

There total 48 articles about 1-Naphthaleneethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

1-(2-bromo)ethylnaphthalene (13686-49-2) → 2-naphthaleneethanol (773-99-9)

Guidance literature:

With water; potassium carbonate; at 110 ℃; for 4.16667h; Green chemistry;

DOI:10.1039/C9RA00590K

Reference yield: 95.0%

methyl 1-naphthylacetate (2876-78-0) → 2-naphthaleneethanol (773-99-9)

Guidance literature:

With sodium tetrahydroborate; In diethylene glycol dimethyl ether; at 114 ℃;

DOI:10.1002/ejoc.200500824

Reference yield: 94.0%

naphth-1-yl acetic acid (86-87-3) → 2-naphthaleneethanol (773-99-9)

Guidance literature:

With tricarbonyl(η(4)-cycloocta-1,5-diene)iron; phenylsilane; In tetrahydrofuran; at 20 ℃; for 24h; chemoselective reaction; Inert atmosphere; UV-irradiation;

DOI:10.1039/c2cc35727e

upstream raw materials:

naphth-1-yl acetic acid

2-(naphthalen-1-yl)ethyl acetate

2-(1,2,3,4-tetrahydronaphthalen-1-yl)ethanol

1-naphthylmagnesiumbromide

Downstream raw materials:

1-vinylnaphthalene

2-α-naphthylethyl chloride

1-(2-bromo)ethylnaphthalene

2-(1-naphthyl)ethyl 4-benzoylbenzoate

Refernces

• 1、 Li, Shaofeng,Nie, Hanyu,Duan, Mengyan,Wang, Wenfei,Zhu, Congjun,Song, Chuanjun. "Construction of a Protoberberine Alkaloid Skeleton via the Palladium-Catalyzed α-Arylation–Amide Formation Cascade". supporting information. p. 9631 - 9634. Retrieved 2021/12/17.
• 2、 Sousa, Sara C. A.,Realista, Sara,Royo, Beatriz. "Bench-Stable Manganese NHC Complexes for the Selective Reduction of Esters to Alcohols with Silanes". . p. 2437 - 2443. Retrieved 2020/04/30.