Dimethoate

Base Information

• Chemical Name: Dimethoate
• CAS No.: 60-51-5
• Deprecated CAS: 11003-53-5,11096-20-1,56833-73-9,79956-18-6,11096-20-1,56833-73-9
• Molecular Formula: C5H12NO3PS2
• Molecular Weight: 229.261
• Hs Code.: 29309090
• European Community (EC) Number: 200-480-3
• ICSC Number: 0741
• UN Number: 2783
• UNII: W6U08B045O
• DSSTox Substance ID: DTXSID7020479
• Nikkaji Number: J1.926G
• Wikipedia: Dimethoate
• Wikidata: Q421371
• NCI Thesaurus Code: C163649
• Metabolomics Workbench ID: 55020
• ChEMBL ID: CHEMBL1569524
• Mol file: 60-51-5.mol

Synonyms:Bi 58;Bi-58;Bi58;Dimethoate;Phosphamide;Rogor

Chemical Property of Dimethoate

Chemical Property:

• Appearance/Colour: white crystalline solid
• Vapor Pressure: 2.5 x 10-4 Pa (25 °C)
• Melting Point: 52-52.5 °C
• Refractive Index: 1.532
• Boiling Point: 107 °C (0.05 torr)
• PKA: 14.40±0.46(Predicted)
• Flash Point: 107 °C
• PSA: 114.76000
• Density: 1.304 g/cm³
• LogP: 2.02440
• Storage Temp.: 0-6°C
• Water Solubility.: Slightly soluble. 2.5 g/100 mL
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 5
• Exact Mass: 228.99962259
• Heavy Atom Count: 12
• Complexity: 191
• Transport DOT Label: Poison

Purity/Quality:

99.9% ^*data from raw suppliers

ANTI-USF2 antibody produced in mouse clone 6A9, purified immunoglobulin, buffered aqueous solution ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn, T, F
• Hazard Codes: Xn,T,F
• Statements: 21/22-63-43-36/37/38-23/24/25-45-36-20/21/22-11-67-40
• Safety Statements: 2-36/37-24/25-23-53-26-16

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Pesticides -> Organophosphate Insecticides
• Canonical SMILES: CNC(=O)CSP(=S)(OC)OC
• Inhalation Risk: Evaporation at 20 °C is negligible; a harmful concentration of airborne particles can, however, be reached quickly.
• Effects of Short Term Exposure: The substance may cause effects on the nervous system at high levels. Cholinesterase inhibition. Exposure could cause death. The effects may be delayed. Medical observation is indicated.
• Effects of Long Term Exposure: Repeated or prolonged contact with skin may cause dermatitis. Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms. Animal tests show that this substance possibly causes toxic effects upon human reproduction.
• Description: Dimethoate is a grey-white crystalline solid at room temperature. It is sparingly soluble in water, soluble in methanol and cyclohexane, but very soluble in chloroform and benzene. It has been classified by the U.S. EPA under GUP. Dimethoate is used extensively for the control of crop pests such as mites, aphids, thrips, plant hoppers, white-flies, and a wide range of other insects that damage, crops, fruits, vegetables, and ornamental plants. Dimethoate is also used for the control of cattle grubs that infect livestock. Thermal decomposition of dimethoate is highly hazardous due to the release of fumes of dimethylsulphide, methyl mercaptan, carbon monoxide, carbon dioxide, phosphorus pentoxide, and nitrogen oxides. Dimethoate is colorless crystalline substance, mp 49 ?C, bp 117 ?C/0.1 mm Hg, vp 0.25 mPa (25 ?C). The solubility in water is 23.8 g/L at 20 ?C and pH 7. It is readily soluble in polar organic solvents. Log Kow = 0.7. Dimethoate is relatively stable in aqueous media at pH 2–7 and hydrolyzed in alkaline media; DT50 (20 ?C) at pH 9 is 12 d.
• Uses: An organophosphate insecticide. It is an anticholinesterase which disables cholinesterase, an enzyme essential for central nervous system function. Neurotoxic in humans. Systemic and contact organophosphorus insecticide and acaricide used to control thrips and red spider mites on many agricultural crops, saw?ies on apples and plums, wheat bulb and olive ?ies. Dimethoate is used to control of a wide range of insect and mite pests in many crops. It is also used to control flies in animal houses. Systemic and contact insecticide.

Technology Process of Dimethoate

There total 6 articles about Dimethoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methylamine (74-89-5) → Dimethoate (60-51-5,79956-18-6)

Guidance literature:

With n-hexan-2-one;

Reference yield:

chloroacetylmethylamide (96-30-0) + potassium O,O-dimethyldithiophosphate (16001-68-6) → Dimethoate (60-51-5,79956-18-6)

Guidance literature:

With acetone;

Reference yield:

2-bromo-N-methylacetamide (34680-81-4) + potassium O,O-dimethyldithiophosphate (16001-68-6) → Dimethoate (60-51-5,79956-18-6)

Guidance literature:

With acetone;

upstream raw materials:

chloroacetylmethylamide

potassium O,O-dimethyldithiophosphate

2-bromo-N-methylacetamide

O,O-Dimethyl-S-(methoxycarbonylmethyl)-dithiophosphat

Downstream raw materials:

O,O-Dimethyl-S-(N-methylcarbamoylmethyl)-dithiophosphorsaeureester-N-nitroso-dimethoat

omethoate

dimethyl S-methyl phosphorodithioate

mercapto-acetic acid methylamide

Refernces

• 1、 -. "SUBSTITUTED SPIROCYCLIC KETOENOLS". . . Retrieved 2008/06/13.
• 2、 -. "Optically active 2,5-bisaryl-delta1-pyrrolines and their use as pest control agents". . . Retrieved 2008/06/13.