Technology Process of (S)-1-benzyl-2-phenoxymethylmorpholine
There total 3 articles about (S)-1-benzyl-2-phenoxymethylmorpholine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2-(benzylamino)ethyl hydrogen sulfate;
With
sodium hydroxide;
In
water;
at 10 - 20 ℃;
for 0.166667h;
(R)-phenyl glycidyl ether;
In
toluene;
at 45 - 50 ℃;
for 15h;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: chlorosulfonic acid / tetrachloromethane / 16 h / 0 - 20 °C
2.1: sodium hydroxide / water / 0.17 h / 10 - 20 °C
2.2: 15 h / 45 - 50 °C
With
chlorosulfonic acid; sodium hydroxide;
In
tetrachloromethane; water;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: tetra(n-butyl)ammonium hydrogensulfate; sodium hydroxide / water / 1 h / 20 - 100 °C
2.1: sodium hydroxide / water / 0.17 h / 10 - 20 °C
2.2: 15 h / 45 - 50 °C
With
tetra(n-butyl)ammonium hydrogensulfate; sodium hydroxide;
In
water;
