- Raltegravir
- Raltegravir potassium
- 518048-06-15-Methyl-[1,3,4]oxadiazole-2-carboxylic acid
- 518051-66-6Nitric acid, strontiumsalt (2:1)
- 51805-42-61-Propanol,3,3',3''-phosphinylidynetris-
- 51805-45-9Propanoic acid,3,3',3''-phosphinylidynetris-, hydrochloride (1:1)
- 518057-64-26-Chloro-2-iodo-3-(trifluoromethyl)pyridine
- 518060-42-9Phenol,3-[(1R)-1-aminoethyl]-
- 518064-28-31H-Imidazole-2-methanamine,5-methyl-
- 518070-19-4Benzoic acid,3-fluoro-5-methyl-
- 518070-24-1Benzoic acid,2-cyano-5-fluoro-
- 518070-26-3Benzeneacetonitrile,2-fluoro-4-methyl-
Hot Products
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
- 7631-86-9Silicon dioxide
- 302-79-4Tretinoin
- 77-92-9Citric acid
|
Basic Information |
|
Post buying leads |
|
Suppliers |
|
Cas Database |
| Name |
Raltegravir |
EINECS | 610-733-3 |
| CAS No. | 518048-05-0 | Density | 1.46 g/cm3 |
| PSA | 152.24000 | LogP | 1.69330 |
| Solubility | N/A | Melting Point |
216 °C(Solv: isopropanol (67-63-0)) |
| Formula | C20H21FN6O5 | Boiling Point | N/A |
| Molecular Weight | 444.422 | Flash Point | N/A |
| Transport Information | N/A | Appearance | N/A |
| Safety | Risk Codes | N/A | |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
5-Hydroxy-2-[1-[[(5-Methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino]-1-methylethyl]-N-(4-fluorobenzyl)-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide;N-(4-Fluorobenzyl)-5-hydroxy-1-methyl-2-[1-methyl-1-[[(5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino]ethyl]-6-oxo-1,6-dihydropyrimidine-4-carboxamide;4-Pyrimidinecarboxamide,N-[(4-fluorophenyl)methyl]-1,6-dihydro-5-hydroxy-1-methyl-2-[1-methyl-1-[[(5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino]ethyl]-6-oxo-; |
Article Data | 23 |
Raltegravir Specification
1. Introduction of Raltegravir
Raltegravir is one kind of white solid. The IUPAC Name of this chemical is N-[2-[(4Z)-4-[[(4-fluorophenyl)methylamino]-hydroxymethylidene]-1-methyl-5,6-dioxopyrimidin-2-yl]propan-2-yl]-5-methyl-1,3,4-oxadiazole-2-carboxamide. Besides, Raltegravir belongs to Antiviral. Raltegravir can soluble in water.
2. Properties of Raltegravir
Physical properties about Raltegravir are:
(1)H bond acceptors: 11; (2)H bond donors: 3; (3)Freely Rotating Bonds: 7; (4)Polar Surface Area: 150.02 Å2; (5)Index of Refraction: 1.65; (6)Molar Refractivity: 110.75 cm3; (7)Molar Volume: 303.4 cm3; (8)Surface Tension: 53.8 dyne/cm; (9)Density: 1.46 g/cm3; (10)XLogP3-AA: 1.1; (11)Rotatable Bond Count: 6; (12)Tautomer Count: 10; (13)Exact Mass: 444.155746; (14)MonoIsotopic Mass: 444.155746; (15)Topological Polar Surface Area: 150; (16)Heavy Atom Count: 32; (17)Formal Charge: 0; (18)Complexity: 836; (19)Isotope Atom Count: 0; (20)Defined Atom Stereocenter Count: 0; (21)Undefined Atom Stereocenter Count: 0; (22)Defined Bond Stereocenter Count: 0; (23)Undefined Bond Stereocenter Count: 0; (24)Covalently-Bonded Unit Count: 1; (25)Feature 3D Acceptor Count: 3; (26)Feature 3D Donor Count: 3; (27)Feature 3D Hydrophobe Count: 1; (28)Feature 3D Ring Count: 3; (29)Effective Rotor Count: 8; (30)Conformer Sampling RMSD: 1.
3. Structure Descriptors of Raltegravir
(1)SMILES: Cc1nnc(o1)C(=O)NC(C)(C)C\3=N\C(C(=O)NCc2ccc(F)cc2)=C(\O)C(=O)N/3C
(2)InChI: InChI=1/C20H21FN6O5/c1-10-25-26-17(32-10)16(30)24-20(2,3)19-23-13(14(28)18(31)27(19)4)15(29)22-9-11-5-7-12(21)8-6-11/h5-8,28H,9H2,1-4H3,(H,22,29)(H,24,30)
(3)InChIKey: CZFFBEXEKNGXKS-UHFFFAOYAM
(4)Std. InChI: InChI=1S/C20H21FN6O5/c1-10-25-26-17(32-10)16(30)24-20(2,3)19-23-13(14(28)18(31)27(19)4)15(29)22-9-11-5-7-12(21)8-6-11/h5-8,28H,9H2,1-4H3,(H,22,29)(H,24,30)
(5)Std. InChIKey: CZFFBEXEKNGXKS-UHFFFAOYSA-N
4. Uses of Raltegravir
Raltegravir (CAS NO.518048-05-0) is drug for treatment of AIDS. Raltegravir (MK-0518, Isentress) is a potent integrase (IN) inhibitor. Raltegravir has entered in a phase II clinical trial in the treatment of HIV infections.
What can I do for you?
Get Best Price
