IARC Cancer Review: Group 3 IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 341.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 42 ,1987,p. 39.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 42 ,1987,p. 39.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Reported in EPA TSCA Inventory.

OSHA PEL: TWA 6 mg/m³
ACGIH TLV: TWA (nuisance particulate) 10 mg/m³ of total dust (when toxic impurities are not present, e.g., quartz <1%)
DFG MAK: 0.3 mg/m³ as fine dust

For occupational chemical analysis use or NIOSH: 1994: silica, amorphous, 7501.

The IUPAC name of Silicic acid(H₂SiO₃) is dihydroxy(oxo)silane. With the CAS registry number 7699-41-4 and EINECS 231-716-3, it is also named as Acidum silicicum. The product's categories are Inorganics; Acids; Electronic Chemicals; Micro / Nanoelectronics; Adsorption / Partition; Protein Chromatography; Silica. It is white amorphous powder or bulk which is insoluble in water or acid, soluble in potassium hydroxide and sodium hydroxide solution. Additionally, this chemical should be sealed in the container and stored in the cool and dry place.

The other characteristics of this product can be summarized as: (1)#H bond acceptors: 3; (2)#H bond donors: 2; (3)#Freely Rotating Bonds: 0; (4)Polar Surface Area: 35.53 Å²; (5)Exact Mass: 77.97732; (6)MonoIsotopic Mass: 77.97732; (7)Topological Polar Surface Area: 57.5; (8)Heavy Atom Count: 4; (9)Formal Charge: 0; (10)Complexity: 26.3; (11)Isotope Atom Count: 0; (12)Covalently-Bonded Unit Count: 1.

Preparation of Silicic acid(H₂SiO₃): Adding a certain amount of sodium silicate (SiO₂ 22.9% ~ 39%, Na₂O 8.6% ~ 14.6%) to the reaction kettle. And then adding a small amount of sulfuric acid to fully dissolve while stirring. Adding a certain amount of aluminum sulfate (Si / Al molar ratio 2:5). Diluted with water to the content of SiO₂ of 0.5% to 1.0%. Finally, after stirring, we can get the product by motionlessness and aging with 1.5h.

Uses of Silicic acid(H₂SiO₃): It is used as coagulant and analytical reagent. It is also used as basic raw materials of powder cosmetics and and toothpaste.

When you are using this chemical, please be cautious about it as the following:
It is irritating to eyes and respiratory system, so people should not breathe dust. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. If you want to contact this product, you must wear suitable protective clothing.

People can use the following data to convert to the molecule structure.
1. SMILES:O=[Si](O)O
2. InChI:InChI=1/H2O3Si/c1-4(2)3/h1-2H
3. InChIKey:IJKVHSBPTUYDLN-UHFFFAOYAA

The following are the toxicity data which has been tested.