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Conditions | Yield |
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In neat (no solvent, solid phase) metal carbonate is reacted with solid SeO2 (fusion); |
This chemical is called Sodium selenite, and its CAS registry number is 10102-18-8. With the classification codes of Human Data; Mutation data; Reproductive Effect; Tumor data, its product categories are Inorganics; Antioxidant Synthetic Reagents; Sodium Neural Stem Cell Biology; Supplements / Reagents; Hybridoma Platform; Serum-free Media; Antioxidant Cancer Research; Chemopreventive Agents; Biochemicals Found in Plants; Inorganic Salts; Nutrition Research; Sodium Metal and Ceramic Science. In addition, this chemical should be sealed in the cool and dry place, away from oxides, acid, fire and heat. Don't keep it with food, seed, feed, all kinds of daily necessities.
Other characteristics of the Sodium selenite can be summarised as followings: (1)#H bond acceptors: 3; (2)#H bond donors: 2; (3)#Freely Rotating Bonds: 0; (4)Polar Surface Area: 57.53 Å2.
Synthesis of this chemcial: Selenium reacts with nitric acid and selenium dioxide. After the removal of nitrogen dioxide, add sodium hydroxide solution. Through the concentrated by heating, dry grinding, you will finally get the Sodium selenite.
Uses of this chemical: The sodium selenite is used as a nutrient enhancer, feed additives, chemical and biological reagents, test alkaloids, testing seed germination. It's also used on a red glass and glaze preparation.
You can still convert the following datas into molecular structure:
1.SMILES: [Na+].[Na+].[O-][Se]([O-])=O
2.InChI: InChI=1/2Na.H2O3Se/c;;1-4(2)3/h;;(H2,1,2,3)/q2*+1;/p-2
3.InChIKey: BVTBRVFYZUCAKH-NUQVWONBAC
The toxicity data is as follows:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
cattle | LDLo | oral | 9900ug/kg (9.9mg/kg) | Journal of the American College of Toxicology. Vol. 5(1), Pg. 45, 1986. | |
chicken | LD50 | parenteral | 8500ug/kg (8.5mg/kg) | Neuropharmacology. Vol. 25, Pg. 493, 1990. | |
dog | LD50 | intravenous | 1916ug/kg (1.916mg/kg) | CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" | Proceedings of the South Dakota Academy of Science. Vol. 36, Pg. 173, 1957. |
dog | LDLo | subcutaneous | 4mg/kg (4mg/kg) | Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975. | |
domestic animals - goat/sheep | LD50 | intramuscular | 1533ug/kg (1.533mg/kg) | SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Veterinary and Human Toxicology. Vol. 29, Pg. 233, 1987. |
domestic animals - goat/sheep | LDLo | oral | 3300ug/kg (3.3mg/kg) | Journal of the American College of Toxicology. Vol. 5(1), Pg. 45, 1986. | |
guinea pig | LD50 | oral | 5060ug/kg (5.06mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 35(2), Pg. 14, 1970. | |
horse/donkey | LD50 | oral | 13mg/kg (13mg/kg) | CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" | American Journal of Veterinary Research. Vol. 41, Pg. 1925, 1980. |
man | TDLo | oral | 24mg/kg (24mg/kg) | GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" GASTROINTESTINAL: NAUSEA OR VOMITING | Veterinary and Human Toxicology. Vol. 39, Pg. 304, 1997. |
mouse | LD50 | intracervical | 300ug/kg (0.3mg/kg) | PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Neurotoxicology. Vol. 2, Pg. 383, 1981. |
mouse | LD50 | intravenous | 5mg/kg (5mg/kg) | PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES CARDIAC: OTHER CHANGES | Neurotoxicology. Vol. 2, Pg. 383, 1981. |
mouse | LD50 | oral | 7080ug/kg (7.08mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 35(2), Pg. 14, 1970. | |
mouse | LD50 | subcutaneous | 13mg/kg (13mg/kg) | Sangyo Igaku. Japanese Journal of Industrial Health. Vol. 17, Pg. 491, 1975. | |
pig | LDLo | intramuscular | 2190ug/kg (2.19mg/kg) | LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" | Journal of the American Veterinary Medical Association. Vol. 165, Pg. 543, 1974. |
pig | LDLo | intravenous | 6570ug/kg (6.57mg/kg) | BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | American Journal of Veterinary Research. Vol. 34, Pg. 1227, 1973. |
pig | LDLo | oral | 13mg/kg (13mg/kg) | Journal of the American College of Toxicology. Vol. 5(1), Pg. 45, 1986. | |
rabbit | LD50 | intramuscular | 2530ug/kg (2.53mg/kg) | Archiv fuer Experimentelle Veterinaermedizin. Vol. 30, Pg. 627, 1976. | |
rabbit | LD50 | oral | 2250ug/kg (2.25mg/kg) | Hygiene and Sanitation Vol. 35(1-3), Pg. 176, 1970. | |
rabbit | LDLo | intraperitoneal | 4mg/kg (4mg/kg) | Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975. | |
rabbit | LDLo | intravenous | 1971ug/kg (1.971mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 33, Pg. 270, 1928. | |
rabbit | LDLo | parenteral | 1971ug/kg (1.971mg/kg) | Clinical Toxicology. Vol. 17, Pg. 171, 1980. | |
rabbit | LDLo | subcutaneous | 6mg/kg (6mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD ENDOCRINE: HYPOGLYCEMIA | Proceedings of the Society for Experimental Biology and Medicine. Vol. 24, Pg. 251, 1926. |
rat | LD50 | intravenous | 3mg/kg (3mg/kg) | Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975. | |
rat | LD50 | oral | 7mg/kg (7mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" | Toxicology and Applied Pharmacology. Vol. 20, Pg. 89, 1971. |
rat | LD50 | parenteral | 6570ug/kg (6.57mg/kg) | Clinical Toxicology. Vol. 17, Pg. 171, 1980. | |
rat | LDLo | intraperitoneal | 5476ug/kg (5.476mg/kg) | BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) LUNGS, THORAX, OR RESPIRATION: CYANOSIS LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Journal of Pharmacology and Experimental Therapeutics. Vol. 58, Pg. 454, 1936. |