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Tiamulin fumarate

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Name Tiamulin fumarate EINECS 259-581-6
CAS No. 55297-96-6 Density
Solubility Melting Point 147-148 °C
Formula C28H47NO4S.C4H4O4 Boiling Point 563 °C at 760 mmHg
Molecular Weight 609.90 Flash Point 294.3 °C
Transport Information UN 2811 6.1/PG 3 Appearance white powder
Safety 36 Risk Codes 22
Molecular Structure Molecular Structure of 55297-96-6 (Tiamulin fumarate) Hazard Symbols HarmfulXn
Synonyms

Tiavet;SQ 22947;Tiamutin;Acetic acid,[[2-(diethylamino)ethyl]thio]-,(3aS,- 4R,5S,6S,8R,9S,9aR,10R)-6-ethenyldecahydro- 5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9- propano-3aH-cyclopentacycloocten-8-yl ester,(2E)-2-butenedioate (1:1) (salt);Dynamutilin;81723hfu;Tiamulin Fumarate Premix;Acetic acid, [[2-(diethylamino)ethyl]thio]-, 6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester, [3aS-(3aα,4β,5α,6α,8β,9α,9aβ,10S*)]-, (E)-2-butenedioate (1:1) (salt);Tiamulin hydrogen fumarate(pleuromutili);Tiamutin Hydrogen Fumarate98%min.;

 

Chemistry

Product Name: Tiamulin fumarate (55297-96-6)
CAS No:55297-96-6
Formula: C32H51NO8S
Molecular Weight: 609.81
Melting Point: 147-148°C
Boiling Point: 563 °C at 760 mmHg
Vapour Pressure: 5.06E-15 mmHg at 25°C
Flash Point: 294.3 °C
Synonyms of Tiamulin fumarate (55297-96-6):  ((2-(Diethylamino)ethyl)thio)acetic acid 8-ester with (3as,4r,5s,6s,8r,9r,9ar,10r)-octahydro-5,8-dihydroxy-4,6,9,10-tetramethyl-6-vinyl-3a,9-propano-3ah-cyclopentacycloocten-1(4h)-one fumarate ; Denagard ; 10-Tetramethyl-1-oxo-3-alpha,9-propano-3-alpha-h-cyclopentacycloocten-8-yles ; 14-Deoxy-14-((2-diethylaminoethyl)-mercaptoacetoxy)-mutilinhydrogenfumarate ; 14-Desossi-14-((2-dietilaminoetil)mercapto-acetossi)mutilinidrogenofumarato ; 81723hfu ; Dynamutilin ; Sandoz81723hfu 
Molecular Structure of Tiamulin fumarate (55297-96-6):

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
chicken LD50 intramuscular 270mg/kg (270mg/kg)   Antimicrobial Agents and Chemotherapy. Vol. 7, Pg. 507, 1975.
 
chicken LD50 oral 1860mg/kg (1860mg/kg)   Antimicrobial Agents and Chemotherapy. Vol. 7, Pg. 507, 1975.
 
mouse LD50 oral 841mg/kg (841mg/kg)   Antimicrobial Agents and Chemotherapy. Vol. 7, Pg. 507, 1975.
 
mouse LD50 subcutaneous 521mg/kg (521mg/kg)   Antimicrobial Agents and Chemotherapy. Vol. 7, Pg. 507, 1975.
 
pigeon LD50 oral 812mg/kg (812mg/kg)   Antimicrobial Agents and Chemotherapy. Vol. 7, Pg. 507, 1975.
 
turkey LD50 intramuscular 409mg/kg (409mg/kg)   Antimicrobial Agents and Chemotherapy. Vol. 7, Pg. 507, 1975.
 
turkey LD50 oral 1345mg/kg (1345mg/kg)   Antimicrobial Agents and Chemotherapy. Vol. 7, Pg. 507, 1975.
 

Safety Profile

Hazard Codes: HarmfulXn
Risk Statements: 22 
R22: Harmful if swallowed
Safety Statements: 36 
S36: Wear suitable protective clothing
RIDADR: UN2811 6.1/PG 3
RTECS: AG9560000

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