- Tazobactam acid
- Tazobactam Diphenylmethyl Ester
- Tazobactam sodium
- 89786-83-42,3,24-Trihydroxy-12-ursen-28-oic acid
- 89787-12-22-Isopropylphenylboronic acid
- 89789-07-14-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, diphenylmethyl ester,4,4-dioxide, (2S,3S,5R)-
- 89792-09-63H-Indazol-3-one,5-amino-1,2-dihydro-
- 89792-11-04H-Pyrrolo[2,3-d]pyrimidin-4-one,3,7-dihydro-2-methyl-
- 897922-06-4Thieno[3,4-b]-1,4-dioxin, 2-(bromomethyl)-2,3-dihydro-
- 89793-11-34-Pyrimidinecarboxylicacid, 2-chloro-6-methyl-, methyl ester
- 89793-12-45-Pyrimidinecarboxylicacid, 2-chloro-, ethyl ester
- 89793-82-81,2-Benzisoxazol-3-amine,5-nitro-
- 89793-83-96-nitrobenzo[d]isoxazol-3-amine
Hot Products
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
- 7631-86-9Silicon dioxide
- 302-79-4Tretinoin
- 77-92-9Citric acid
|
Basic Information |
|
Post buying leads |
|
Suppliers |
|
Cas Database |
| Name |
Tazobactam acid |
EINECS | 618-303-7 |
| CAS No. | 89786-04-9 | Density | 1.92 g/cm3 |
| PSA | 127.43000 | LogP | -0.40470 |
| Solubility | Soluble in water | Melting Point |
115-145℃ |
| Formula | C10H12N4O5S | Boiling Point | 707.1 °C at 760 mmHg |
| Molecular Weight | 300.295 | Flash Point | 381.4 °C |
| Transport Information | N/A | Appearance | White or off-white powder |
| Safety | 26-36 | Risk Codes | 36/37/38 |
| Molecular Structure |
|
Hazard Symbols |
 Xi
|
| Synonyms |
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, [2S-(2a,3b,5a)]-;CL 298741;Tazobactam;YTR 830H;4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, (2S,3S,5R)-; |
Article Data | 19 |
Tazobactam acid Chemical Properties
The Molecular Structure of Tazobactam acid (CAS NO.89786-04-9):
Empirical Formula: C10H12N4O5S
Molecular Weight: 300.2911
Nominal Mass: 300 Da
Average Mass: 300.2911 Da
Monoisotopic Mass: 300.05284 Da
Index of Refraction: 1.817
Molar Refractivity: 67.65 cm3
Molar Volume: 155.7 cm3
Surface Tension: 97.3 dyne/cm
Density: 1.92 g/cm3
Flash Point: 381.4 °C
Enthalpy of Vaporization: 108.6 kJ/mol
Boiling Point: 707.1 °C at 760 mmHg
Vapour Pressure: 5.55E-21 mmHg at 25°C
Appearance: White or off-white powder
Product Categories: Amino Acid Derivatives;Peptide Synthesis/Antibiotics
IUPAC: (2S,3S,5R)-3-methyl-4,4,7-trioxo-3-(triazol-1-ylmethyl)-4$l^{6}-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Synonyms: Tazobactam ; Tazobactam [USAN:INN:BAN] ; Zosyn ; (2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 4,4-dioxide ; 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, (2S-(2alpha,3beta,5alpha))- ; BRN 4787943 ; CCRIS 2203 ; CL 298,741 ; Cl 298741 ; Tazobactam ; Tazobactamum [INN-Latin] ; UNII-SE10G96M8W
Tazobactam acid Uses
Tazobactam acid (CAS NO.89786-04-9) is able to inhibit the most common forms of beta-lactamase, but is not able to interact with the ampC cephalosporinase. Thus, it confers little protection against bacteria such as Pseudomonas aeruginosa, Citrobacter, Enterobacter, and Serratia, which often express this gene.In the United States, sulbactam(89786-04-9) is combined to form cefoperazone/sulbactam and ampicillin/sulbactam. It does possess some antibacterial activity when administered alone, but it is too weak to have any clinical importance. Its use in the UK is restricted to hospitals.
Tazobactam acid Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| dog | LD50 | intravenous | > 5gm/kg (5000mg/kg) | LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" KIDNEY, URETER, AND BLADDER: HEMATURIA | Journal of Toxicological Sciences. Vol. 19(Suppl, |
| mouse | LD50 | intraperitoneal | > 5gm/kg (5000mg/kg) | SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Journal of Toxicological Sciences. Vol. 19(Suppl, |
| mouse | LD50 | intravenous | > 5gm/kg (5000mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Journal of Toxicological Sciences. Vol. 19(Suppl, |
| mouse | LD50 | oral | > 5gm/kg (5000mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Journal of Toxicological Sciences. Vol. 19(Suppl, |
| mouse | LD50 | subcutaneous | > 5gm/kg (5000mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" | Journal of Toxicological Sciences. Vol. 19(Suppl, |
| rat | LD50 | intraperitoneal | > 5gm/kg (5000mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" | Journal of Toxicological Sciences. Vol. 19(Suppl, |
| rat | LD50 | intravenous | > 5gm/kg (5000mg/kg) | SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Journal of Toxicological Sciences. Vol. 19(Suppl, |
| rat | LD50 | oral | > 5gm/kg (5000mg/kg) | SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" | Journal of Toxicological Sciences. Vol. 19(Suppl, |
| rat | LD50 | subcutaneous | > 5gm/kg (5000mg/kg) | SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" | Journal of Toxicological Sciences. Vol. 19(Suppl, |
low toxicity--DL50 i.p. in mice over 4,000 mg/kg
Tazobactam acid Safety Profile
Hazard Codes: 
Xi
Risk Statements: 36/37/38
R36/37/38: Irritating to eyes, respiratory system and skin
Safety Statements: 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36: Wear suitable protective clothing
What can I do for you?
Get Best Price
