Basic information
- Name:
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, sodium salt(1:1), (2S,3S,5R)-
- Superlist Name:
- Tazobactam sodium
- CAS No.:
89785-84-2
- Molecular Structure:
![Molecular Structure of 89785-84-2 (4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, sodium salt(1:1), (2S,3S,5R)-)](http://www.lookchem.com/300w\2011-9\2e64d43e-a663-4462-bd8d-cd51e066ed83.gif)
- Formula:
- C10H12N4O5S . Na
- Molecular Weight:
- 322.27
- Deleted CAS:
- 93528-38-2
- Synonyms:
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, sodiumsalt, (2S,3S,5R)- (9CI);4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, sodium salt,[2S-(2a,3b,5a)]-;CL 307579;Tazobactam sodium;YTR 830;
- Boiling Point:
- 707.1 °C at 760 mmHg
- Flash Point:
- 381.4 °C
- Safety Description:
- 22-24/25 Details
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Chemistry
MF: C20H19N4NaO5S
MW: 450.44
mp: 140-147°C
storage temp: Store at 0-5°C
solubility: H2O: 50 mg/mL, clear, colorless
CAS DataBase Reference: 89785-84-2(CAS DataBase Reference)
NIST Chemistry Reference:89785-84-2 (NIST)
The structure of Tazobactam sodium is:
Uses
1、Tazobactam sodium is mainly used as lactamase inhibitor and it also used with lactam antibiotics to enhance their effect.
2、It is added to the extended spectrum beta-lactam antibiotic piperacillin to produce Tazocin or Zosyn or Piprataz (manufactured by Gepach International). It broadens the spectrum of piperacillin by making it effective against organisms that express beta-lactamase and would normally degrade piperacillin.
3、Tazobactam sodium is a derivative of the penicillin nucleus and is a penicillanic acid sulfone.
Consensus Reports
Safety Profile
Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 22-24/25-36-26
WGK Germany: 3
RTECS: XI0191500