- Tazobactam acid
- Tazobactam Diphenylmethyl Ester
- Tazobactam sodium
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- 89789-07-14-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, diphenylmethyl ester,4,4-dioxide, (2S,3S,5R)-
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Cas Database |
| Name |
Tazobactam sodium |
EINECS | 685-629-4 |
| CAS No. | 89785-84-2 | Density | 1.92 g/cm3 |
| PSA | 133.67000 | LogP | -1.83920 |
| Solubility | Soluble in water.Soluble in water and methanol. | Melting Point |
140-147oC |
| Formula | C10H12N4O5S . Na | Boiling Point | 707.1 °C at 760 mmHg |
| Molecular Weight | 322.277 | Flash Point | 381.4 °C |
| Transport Information | N/A | Appearance | N/A |
| Safety | 22-24/25 | Risk Codes | 36/37/38 |
| Molecular Structure |
|
Hazard Symbols | Xi |
| Synonyms |
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, sodiumsalt, (2S,3S,5R)- (9CI);4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, sodium salt,[2S-(2a,3b,5a)]-;CL 307579;Tazobactam sodium;YTR 830; |
Article Data | 4 |
Tazobactam sodium Chemical Properties
MF: C20H19N4NaO5S
MW: 450.44
mp: 140-147°C
storage temp: Store at 0-5°C
solubility: H2O: 50 mg/mL, clear, colorless
CAS DataBase Reference: 89785-84-2(CAS DataBase Reference)
NIST Chemistry Reference:89785-84-2 (NIST)
The structure of Tazobactam sodium is:
Tazobactam sodium Uses
1、Tazobactam sodium is mainly used as lactamase inhibitor and it also used with lactam antibiotics to enhance their effect.
2、It is added to the extended spectrum beta-lactam antibiotic piperacillin to produce Tazocin or Zosyn or Piprataz (manufactured by Gepach International). It broadens the spectrum of piperacillin by making it effective against organisms that express beta-lactamase and would normally degrade piperacillin.
3、Tazobactam sodium is a derivative of the penicillin nucleus and is a penicillanic acid sulfone.
Tazobactam sodium Consensus Reports
Tazobactam sodium Safety Profile
Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 22-24/25-36-26
WGK Germany: 3
RTECS: XI0191500
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