José Mario Molina-Pasquel Henríquez (born March 19, 1943 in Mexico City) is a Mexican chemist and one of the most prominent precursors to the discovering of the Antarctic ozone hole. He was a co-recipient (along with Paul J. Crutzen and F. Sherwood Rowland) of the 1995 Nobel Prize in Chemistry for his role in elucidating the threat to the Earth's ozone layer of chlorofluorocarbon gases (or CFCs), becoming the first Mexican-born citizen to ever receive a Nobel Prize in Chemistry.

After completing his basic studies in Mexico City and Switzerland he earned a bachelor's degree in Chemical Engineering at the National Autonomous University of Mexico in 1965, a postgraduate degree from the Albert Ludwigs University of Freiburg, West Germany, in 1967 and a doctoral degree in Chemistry from University of California, Berkeley in 1972.
In 1974, as a postdoctoral researcher at UC Irvine, he and Rowland co-authored a paper in the journal Nature highlighting the threat of CFCs to the ozone layer in the stratosphere.
This led to moves towards the worldwide elimination of CFCs from aerosol cans and refrigerators, and it is for this work that Molina later shared the Nobel Prize in Chemistry.
Between 1974 and 2004 he variously held research and teaching posts at UC Irvine, the Jet Propulsion Laboratory at Caltech and the Massachusetts Institute of Technology (MIT), where he held a joint appointment in the Department of Earth Atmospheric and Planetary Sciences and the Department of Chemistry.
On July 1, 2004 Molina joined the Department of Chemistry and Biochemistry at University of California, San Diego and the Center for Atmospheric Sciences at the Scripps Institution of Oceanography.