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Venlafaxine

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Venlafaxine

EINECS 618-944-2
CAS No. 93413-69-5 Density 1.06 g/cm3
PSA 32.70000 LogP 3.03560
Solubility <0.1g/L(room temperature) Melting Point 72-74 °C
Formula C17H27NO2 Boiling Point 397.6 °C at 760 mmHg
Molecular Weight 277.407 Flash Point 194.2 °C
Transport Information N/A Appearance White solid
Safety Risk Codes R36/37/38; R20/22
Molecular Structure Molecular Structure of 93413-69-5 (Venlafaxine) Hazard Symbols Xn
Synonyms

Cyclohexanol,1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]-, (?à)-;Trevilor;Velafax;Venlafaxin;Venlafaxine;Venlafaxine XR;Venlafexine;

Article Data 56

Venlafaxine Specification

 The Venlafaxine with the cas number 93413-69-5, is also called (1)Elafax ; (2)Venlafaxina ; (3)Venlafaxine ; (4)Venlafaxinum ; (5)Cyclohexanol, 1-(2-(dimethylamino)-1-(4-methoxyphenyl)ethyl)-, (+-)- . It belongs to the following Product Categories such as:(1)Pharmaceutical material and intermeidates; (2)Venlafaxine; (3)Chiral Reagents; (4)Inhibitors; (5)Intermediates & Fine Chemicals; (6)Pharmaceuticals

Properties of Venlafaxine are: (1)ACD/BCF (pH 5.5): 1 ; (2)ACD/BCF (pH 7.4): 1.84 ; (3)ACD/KOC (pH 5.5): 1 ; (4)ACD/KOC (pH 7.4): 17.49 ; (5)#H bond acceptors: 3 ; (6)#H bond donors: 1 ; (7)#Freely Rotating Bonds: 6 ; (8) Polar Surface Area: 21.7Å2 ; (9)Index of Refraction: 1.544 ; (10) Molar Refractivity: 82.63 cm3 ; (11)Molar Volume: 261.6 cm3 ; (12) Polarizability: 32.75 ×10-24cm3 ; (13)Surface Tension: 41.1 dyne/cm ; (14)Density: 1.06 g/cm3 ; (15)Flash Point: 194.2 °C ; (16)Enthalpy of Vaporization: 68.34 kJ/mol ; (17)Boiling Point: 397.6 °C at 760 mmHg ; (18)Vapour Pressure: 4.92E-07 mmHg at 25°C

The Venlafaxine is used for Various types of depression include depression with anxiety and generalized anxiety disorder. Venlafaxine has many common side effects: gastrointestinal upset (nausea, thirst, anorexia, constipation and vomiting), central nervous system abnormality (vertigo, drowsiness, monstrous dreams, insomnia and nervous), paropsia, abnormal sweating and yawning, sexual dysfunction (impotence, abnormal ejaculation, decreased libido). occasional adverse reactions are weak, flatulence, tremor and excited, diarrhea, rhinitis. Adverse reactions often occur in the initial stage treatment. As treatment continues, these side effects would gradually subsided. Venlafaxine has no obvious drug dependence.

You can still convert the following datas into molecular structure :
1. SMILES: OC2(C(c1ccc(OC)cc1)CN(C)C)CCCCC2
2. InChI: InChI=1/C17H27NO2/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14/h7-10,16,19H,4-6,11-13H2,1-3H3

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