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CAS No.: | 115-37-7 |
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Name: | THEBAINE |
Article Data: | 41 |
Molecular Structure: | |
Formula: | C19H21 N O3 |
Molecular Weight: | 311.381 |
Synonyms: | Morphinan,6,7,8,14-tetradehydro-4,5a-epoxy-3,6-dimethoxy-17-methyl- (8CI); (-)-Thebaine; Paramorphine;Thebain; Thebaine |
Density: | 1.3g/cm3 |
Melting Point: | 183-186°C (dec.) |
Boiling Point: | 467.6°Cat760mmHg |
Flash Point: | 141°C |
Solubility: | <10mg/L(room temperature) |
Hazard Symbols: | Toxic by ingestion, may induce addiction. |
Risk Codes: | 26/27/28 |
Safety: | Poison by subcutaneous, intravenous, and intraperitoneal routes. Its action on humans resembles that of strychnine. When heated to decomposition it emits highly toxic fumes of NOx. |
PSA: | 30.93000 |
LogP: | 2.36240 |
Product Name: Thebaine
Synonyms: Paramorphine ; Thebaine ; (-)-Thebain ; 6,7,8,14-Tetradehydro-4,5-alpha-epoxy-3,6-dimethoxy-17-methyl-morphina ; 6,7,8,14-Tetradehydro-4,5-epoxy-3,6-dimethoxy-17-methyl-morphina-4,5-alpha ; Morphinan, 6,7,8,14-tetradehydro-4,5alpha-epoxy-3,6-dimethoxy-17-methyl-; Morphinan, 6,7,8,14-tetradehydro-4,5-epoxy-3,6-dimethoxy-17-methyl-, (5alpha)- ; Tebain
CAS: 115-37-7
MolecularFormula: C19H21NO3
Molecular Weight:311.37
Molecular Struture:
EINECS: 204-084-1
Form : powder
Surface Tension: 53.8 dyne/cm
Density: 1.3 g/cm3
Flash Point: 141 °C
Enthalpy of Vaporization: 72.97 kJ/mol
Boiling Point: 467.6 °C at 760 mmHg
Vapour Pressure: 6.4E-09 mmHg at 25°C
Solubility: H2O: 2.2 mg/mL, slightly soluble
Pharmacological effects of Thebaine (115-37-7) is contrary to morphine, it's spasm toxic exceed over effectnarcotic effect. cold-blooded animals are excited about reflection, in the dogs body also showed a similar response to morphine anesthesia.
1. | ipr-mus LD50:42 mg/kg | AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. 132 (1961),255. | ||
2. | scu-mus LD50:31 mg/kg | 28ZNAE “Public Health Reports, Supplement.“ 138 (1938),31. | ||
3. | scu-rbt LD50:13.9 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 66 (1939),182. | ||
4. | ivn-rbt LD50:3 mg/kg | AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. 132 (1961),255. |
Hazard Codes T+
Risk Statements 26/27/28
26/27/28: Thebaine (115-37-7) is very toxic by inhalation, in contact with skin and if swallowed
Safety Statements 22-36/37/39-45
22: Do not breathe dust
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
36/37/39: Thebaine (115-37-7) used, wear suitable protective clothing, gloves and eye/face protection
RIDADR UN 1544 6.1/PG 2
WGK Germany 3
RTECS QD2975000
HazardClass 6.1(b)
PackingGroup III