Welcome to LookChem.com Sign In|Join Free

Products

  • or
Home > Pharmaceutical > 124858 > 

124858-35-1

Refine

Refine

Country

Business Type

Certificate

Display

Basic Information
CAS No.: 124858-35-1
Name: Nadifloxacin
Article Data: 2
Molecular Structure:
Molecular Structure of 124858-35-1 (Nadifloxacin)
Formula: C19H21FN2O4
Molecular Weight: 360.385
Synonyms: 1H,5H-Benzo[ij]quinolizine-2-carboxylic acid, 9-fluoro-6,7-dihydro-8-(4-hydroxy-1-piperidinyl)-5-methyl-1-oxo-, (±)-;Jinofloxacin;OPC 7251;
EINECS: 638-863-6
Density: 1.467 g/cm3
Melting Point: 245-247 °C
Boiling Point: 624.891 °C at 760 mmHg
Flash Point: 331.722 °C
Appearance: off-white crystalline solid
PSA: 82.77000
LogP: 2.37210
Synthetic route
5382-16-1

4-HYDROXYPIPERIDINE

77483-92-2

9-fluoro-8-bromo-5-methyl-6,7-dihydro-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acid

124858-35-1

nadifloxacin

Conditions
ConditionsYield
In N,N,N,N,N,N-hexamethylphosphoric triamide at 160℃; for 7h;25%
1128-61-6

6-fluoro-2-methyl-quinoline

124858-35-1

nadifloxacin

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 87 percent / Br2, Ag2SO4, cc H2SO4, / 1 h
2: 68 percent / H2, / PtO2, / acetic acid / Ambient temperature
3: 2.) PPA, 3.) cc HCl, / 1.) 150 deg C, 1 h, 2.) 150 deg C, 30 min, 3.) AcOH, H2O, reflux, 2 h,
4: 25 percent / hexamethylphosphoric acid triamide / 7 h / 160 °C
View Scheme
80290-18-2

5-bromo-6-fluoro-2-methylquinoline

124858-35-1

nadifloxacin

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 68 percent / H2, / PtO2, / acetic acid / Ambient temperature
2: 2.) PPA, 3.) cc HCl, / 1.) 150 deg C, 1 h, 2.) 150 deg C, 30 min, 3.) AcOH, H2O, reflux, 2 h,
3: 25 percent / hexamethylphosphoric acid triamide / 7 h / 160 °C
View Scheme
79085-71-5

5-bromo-6-fluoro-2-methyl-1,2,3,4-tetrahydroquinoline

124858-35-1

nadifloxacin

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 2.) PPA, 3.) cc HCl, / 1.) 150 deg C, 1 h, 2.) 150 deg C, 30 min, 3.) AcOH, H2O, reflux, 2 h,
2: 25 percent / hexamethylphosphoric acid triamide / 7 h / 160 °C
View Scheme
124858-35-1

nadifloxacin

74-88-4

methyl iodide

129672-74-8

methyl-9-fluoro-6,7-dihydro-8-(4-hydroxy-1-piperidyl)-5-methyl-1-oxo-1H,5H-benzoquinolizine-2-carboxylate

Conditions
ConditionsYield
With potassium hydroxide In N,N,N,N,N,N-hexamethylphosphoric triamide; ethanol at 60℃; for 1.5h;91%
1201939-89-0

4-((6,7-dimethoxyquinazolin-4-yl)oxy)-3-fluoroaniline

124858-35-1

nadifloxacin

N-(4-((6,7-dimethoxyquinazolin-4-yl)oxy)-3-fluorophenyl)-9-fluoro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1,5,6,7-tetrahydropyrido[3,2,1-ij]quinoline-2-carboxamide

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃;70%
124858-35-1

nadifloxacin

64-19-7

acetic acid

81962-90-5

8-(4-acetoxy-1-piperidyl)-9-fluoro-6,7-dihydro-5-methyl-1-oxo-1H,5H-benzoquinolizine-2-carboxylic acid

Conditions
ConditionsYield
With sulfuric acid In dichloromethane for 5h; Heating;57%
124858-35-1

nadifloxacin

80441-55-0

6-(S-tritylmercapto)hexanoic acid

1398623-75-0

C44H45FN2O5S

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 22℃; for 13h; Inert atmosphere;24%
124858-35-1

nadifloxacin

130539-79-6

9-fluoro-6,7-dihydro-5-methyl-8-(4-sulfoxy-1-piperidyl)-1-oxo-1H,5H-benzoquinolizine-2-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 91 percent / 85percent potassium hydroxide / hexamethylphosphoric acid triamide; ethanol / 1.5 h / 60 °C
2: 1) chlorosulfonic acid / 1) 50-55 deg C, 30 min, 2a) 50-55 deg C, 6 h, 2b) r.t., overnight
3: 38 percent / 0.1N KOH / methanol
View Scheme
124858-35-1

nadifloxacin

130539-78-5

pyridinium 9-fluoro-6,7-dihydro-8-(4-hydroxy-1-piperidyl)-2-methoxycarbonyl-5-methyl-1-oxo-1H,5H-benzoquinolizine sulfate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 91 percent / 85percent potassium hydroxide / hexamethylphosphoric acid triamide; ethanol / 1.5 h / 60 °C
2: 1) chlorosulfonic acid / 1) 50-55 deg C, 30 min, 2a) 50-55 deg C, 6 h, 2b) r.t., overnight
View Scheme
  • Display:default sort

    New supplier

  • Nadifloxacin

  • Casno:

    124858-35-1

    Nadifloxacin

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 3.0-3.0

    DayangChem exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product s

    Dayang Chem (Hangzhou) Co.,Ltd. dedicated to the development, production and marketing of chemicals which is specialized in Organic compounds; Active Pharmaceutical Ingredi

  •  Dayang Chem (Hangzhou) Co.,Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-571-88938639

    Address:9/F, Unit 2 Changdi Torch Building, 259# WenSan Road, Xihu District, Hangzhou City 310012, P.R.China

       Inquiry Now

  • High quality Nadifloxacin supplier in China

  • Casno:

    124858-35-1

    High quality Nadifloxacin supplier in China

    Min.Order: 0 Metric Ton

    FOB Price:  USD $ 0.0-0.0

    Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

    Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional

  •  Simagchem Corporation

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:+86-592-2680277

    Address:21/F Hualong Office Building,No.6 Hubin East Road, Xiamen,China

       Inquiry Now

  • High quality Nadifloxacin CAS 124858-35-1 with fatory price

  • Casno:

    124858-35-1

    High quality Nadifloxacin CAS 124858-35-1 with fatory price

    Min.Order: 0 Metric Ton

    FOB Price:  USD $ 0.0-0.0

    1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; ...... Appearance:White Powder Storage:-20°C Package:1kg/foil bag; 1kg/tin

    Wuhan Fortuna Chemical Co., Ltd, located in the predominant Wu Han City where is a traffic hinge of China, is a big integrative chemical enterprise being engaged in producing and

  •  Wuhan Fortuna Chemical Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86-27-59207852

    Address:Add: Room 2015, No.2 Building, Kaixin Mansion No.107 Jinqiao Avenue, Wuhan, China

       Inquiry Now

  • Nadifloxacin Price

  • Casno:

    124858-35-1

    Nadifloxacin Price

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 2.0-3.0

    Nadifloxacin English name: Nadifloxacin Chemical name: 9-fluoro-6,7-dihydro-8-(4-hydroxy-1-Piperidinyl)-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acid Category involved:

    Founded in 2008, East Chemsources Limited is a professional manufacturer of supplier in food and beverage, pharmaceuticals, cosmetics and other industries. pharmaceutical field in

  •  EAST CHEMSOURCES LIMITED

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:86-532-81906761

    Address:No.1581-12,Jinshui Road, Licang, Qingdao,China

       Inquiry Now

  • Factory Supply Nadifloxacin

  • Casno:

    124858-35-1

    Factory Supply Nadifloxacin

    Min.Order: 1

    FOB Price:  USD $ 0.0-0.0

    The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

    Ality Chemical, established in 2007, is a comprehensive Chemical Production&Supply Group with Patent Technology as its core. Ality Chemical operates sales branches in Shanghai, Xia

  •  Ality Chemical Corporation

     China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:0513-87616220

    Address:Fine chemical industry park, Nantong,Jiangsu

       Inquiry Now

  • Factory Price API 99% Nadifloxacin 124858-35-1 GMP Manufacturer

  • Casno:

    124858-35-1

    Factory Price API 99% Nadifloxacin 124858-35-1 GMP Manufacturer

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.1-0.1

    1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

    Xi'an Xszo Chem Co. Ltd is a wholly-owned subsidiary of the SZO Chem Group. SZO Group is composed of Xi'an Xszo Chem Co. Ltd & Shaanxi SZO Tech Co., Ltd. SZO industry Group have mo

  •  Xi'an Xszo Chem Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:+86-029-88698540

    Address:No.16,Jingqin Rd. JingWei Industrial park,Shaanxi,China,710200

       Inquiry Now

  • Nadifloxacin

  • Casno:

    124858-35-1

    Nadifloxacin

    Min.Order: 10 Milligram

    FOB Price:  USD $ 0.0-0.0

    1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

    Founded in 2011, Amadis Chemical Company Limited is an innovative manufacturer of chemical products and technical service providers. Our business includes sales, manufacture, and s

  •  Amadis Chemical Co., Ltd.

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-571-89925085

    Address:Watts Cosine.No.166.Xiangmao Road.

       Inquiry Now

  • Nadifloxacin

  • Casno:

    124858-35-1

    Nadifloxacin

    Min.Order: 5 Kiloliter

    FOB Price:  USD $ 1.2-5.0

    Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

    Our main production base is located in Xuzhou industry park. We produce a wide range of organics including Fine chemicals, Active pharmaceutical ingredients(APIs), Veterinary, In

  •  Chemwill Asia Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:021-51086038

    Address:High-Tech Industrial park,Chemical Economical Development Zone,Xuzhou, Jiangsu-Province, P.R.China

       Inquiry Now

  • Nadifloxacin CAS 124858-35-1

  • Casno:

    124858-35-1

    Nadifloxacin CAS 124858-35-1

    Min.Order: 1 Gram

    FOB Price:  USD $ 6.0-9.0

    With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

    Our company specializes in processing and selling chemical raw materials, chemical th Asia, Europe, America, Africa and other more than 20 countries and regions. ? Companies adheri

  •  Hebei Nengqian Chemical Import and Export Co., LTD

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86 13910575315

    Address:hebei

       Inquiry Now

  • New production CAS 124858-35-1 with best quality

  • Casno:

    124858-35-1

    New production CAS 124858-35-1 with best quality

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 139.0-210.0

    WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

    Zhuo Zhou Wen Xi Import and Export Co., Ltd. is a company mainly engaged in the export of pharmaceutical raw materials. Its parent company is (Wen Xi Pharma), including three subs

  •  Zhuozhou Wenxi import and Export Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-13111626072

    Address:Room 1710, Baoxin International Phase I, 19 Guanyun East Road, Zhuozhou, Hebei

       Inquiry Now

  • Nadifloxacin,124858-35-1

  • Casno:

    124858-35-1

    Nadifloxacin,124858-35-1

    Min.Order: 1 Metric Ton

    FOB Price:  USD $ 1.0-1.0

    124858-35-1 Nadifloxacin product Name Nadifloxacin Synonyms (±)-9-Fluoro-6,7-dihydro-8-(4-hydroxy-1-piperidinyl)-5-methyl-1-oxo-1H,5H-b

    Welcome to Henan Sinotech! Sinotech Corporation has exceptional sourcing ability for chemicals used in Organic Fine Chemicals and APIs; Inorganic chemicals; Flame Retardants;OLED

  •  Henan Sinotech Import&Export Corporation

     China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:86-371-86181678

    Address:No. 260, Dongming Road,Jinshui District

       Inquiry Now

  • Nadifloxacin factory price

  • Casno:

    124858-35-1

    Nadifloxacin factory price

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 1.0-1.0

    Appearance:White to yellow powder Storage:Sealed in dry,Store in freezer, under -20°C Package:25kg/drum Application:Nadifloxacin is a topical fluorinated quinolone antibacterial used to treat skin conditions such as acne and other dermal infections

    Founded in 2005, Sartort, located in Hangzhou, is a leading company engaging in chemistry, pharmaceutical and advanced materials. At present, Sartort has such controlled subsidi

  •  Hangzhou Sartort Biopharma Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-571-87039693

    Address:No. 57, Tech Park Road, Hangzhou, Zhejiang, China

       Inquiry Now

  • 99%min Nadifloxacin Manufcturer For Treatment Acne

  • Casno:

    124858-35-1

    99%min Nadifloxacin Manufcturer For Treatment Acne

    Min.Order: 10 Gram

    FOB Price:  USD $ 0.0-0.0

    Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best serv

    Hubei Langyou International Trading Co., Ltd. dedicated to the development, production and marketing of chemicals which is specialized in Organic compounds; Active Pharmaceutical I

  •  Wuhan 90000 Lithium Industry and Trade Co., Ltd.

    China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-027-83214688

    Address:No.43, Xinandu Industrial Park, East and West Lake District, Wuhan, Hubei, China

       Inquiry Now

  • Nadifloxacin

  • Casno:

    124858-35-1

    Nadifloxacin

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0

    1.Prompt Goods; 2.Flexible payment terms; 3.Documents & Certificate support. Name: Nadifloxacin Structure: Formula: C19H21FN2O4 Molecular Weight : 638-863-6 Synonyms: NDFX;Nadifiloxacin;NadifloxacinAPI;7-fluoro-8-(4-hydroxypiperidin-1-yl)

    Hubei Hanways Pharmchem Co.,Limited is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. Now we

  •  HANWAYS CHEMPHARM CO.,LIMITED

    China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-18502787239(whatsapp)

    Address:18-1-802, Green Garden, Jianghan District, Wuhan 430023, China

       Inquiry Now

  • Nadifloxacin  99%

  • Casno:

    124858-35-1

    Nadifloxacin 99%

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 45.0-56.0

    Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

    Baoji Guokang Healthchem co.,ltd located in Baoji High-tech Zone,is epitomizing international,cooperative and honest.We are a young company full of action and energy,and our profes

  •  Baoji Guokang Healthchem co.,ltd

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86-917-3909592

    Address:China

       Inquiry Now

  • Nadifloxacin CAS:124858-35-1

  • Casno:

    124858-35-1

    Nadifloxacin CAS:124858-35-1

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0

    Nadifloxacin CAS:124858-35-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediat

    Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, speciali

  •  Qingdao Beluga Import and Export Co., LTD

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+8613854236000

    Address:qingdao

       Inquiry Now

  • Nadifloxacin

  • Casno:

    124858-35-1

    Nadifloxacin

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0

    Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

    AFINE CHEMICALS LIMITED is specialized in the fine chemicals and pharmaceuticals and we have enjoyed great popularity in world markets. Since 2005, we have been rapidly growing to

  •  Afine Chemicals Limited

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-571-85134551

    Address:No. 206 Zhen Hua Road, Hangzhou 310030, Zhejiang, China

       Inquiry Now

  • Nadifloxacin

  • Casno:

    124858-35-1

    Nadifloxacin

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0

    Our product has a very high quality and now we are exporting to customers overseas with very positive feedback. With best price, quality and service from Nanjing Sunny, we are confident to set up a very nice cooperation with customers all over the w

    Welcome to Sunny Pharmatech! Nanjing Sunny pharmatech Co., Ltd is a manufacturer and supplier of raw materials and ingredients for food and healthy supplement products, intermediat

  •  NANJING SUNNY PHARMATECH CO., LTD

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86-13814179829

    Address:No. 1704 SHUANGLONOG AVENUE, NANJING, CHINA

       Inquiry Now

  • nadifloxacin 124858-35-1

  • Casno:

    124858-35-1

    nadifloxacin 124858-35-1

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0

    Our company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-

    Taizhou Crene Biotechnology Co., Ltd.is a leading supplier of active pharmaceutical ingredients (APIs), with GLP labs and GMP manufacturing facilities engaging in organic synthesis

  •  Taizhou Crene Biotechnology co.ltd

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-576-88813233 88205808

    Address:Economic Developed Zone of Taizhou Zhejiang China

       Inquiry Now

  • Nadifloxacin

  • Casno:

    124858-35-1

    Nadifloxacin

    Min.Order: 0 Metric Ton

    FOB Price:  USD $ 0.0-0.0

    Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

    Hangzhou Keying Chem Co., Ltd. Is a comprehensive enterprise, dedicated to the development, production and marketing of chemicals. As a technology innovative and service profession

  •  Hangzhou Keyingchem Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-571-85378921

    Address:Jintong international Building, No.113,Huayuangang Street, Gong shu District, Hangzhou,Zhejiang, China.

       Inquiry Now

  • Nadifloxacin

  • Casno:

    124858-35-1

    Nadifloxacin

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0

    Hello, dear friend! Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by email in time. product quality 1.The product quality h

    Suzhou senfeida Chemical Co., Ltd. is located in Hushuguan economic and Technological Development Zone, Suzhou high tech Zone. It is a civilian chemical enterprise that produces an

  •  Suzhou Senfeida Chemical Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:186-624-33356

    Address:Hushuguan Economic and Technological Development Zone, Suzhou High-tech Zone

       Inquiry Now

  • Nadifloxacine

  • Casno:

    124858-35-1

    Nadifloxacine

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

    J&H Chemical is one of China's leading providers of integrated fine chemical services including offering, research and development, Custom manufacturing business, as well as other

  •  Hangzhou J&H Chemical Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-571-87396432

    Address:No.200 Zhenhua Rd.Xihu Industrial Park, Hangzhou 310030, China

       Inquiry Now

  • Nadifloxacin

  • Casno:

    124858-35-1

    Nadifloxacin

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0

    Quatlity Assurance We are a GMP compliance manufacturer with over 20 years experience, We make strictly quality contral according to EU guidelines on Good Manufacturing Practice for Active Substances used as Starting Materials. VQ and plant audit ar

    Founded in 2007, Finetech is a high-tech enterprise focusing on the research and development, production and CDMO services of functional chemicals, KSMs, intermediates and APIs. Fi

  •  Nanjing Finetech Chemical Co., Ltd.

    China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:0086-25-52078417

    Address:No.9 Weidi Road Jiangsu Life-science High-tech Zone, 210046, Nanjing China.

       Inquiry Now

  • Nadifloxacin

  • Casno:

    124858-35-1

    Nadifloxacin

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0

    1) Quick response within 2 hours; 2) Quality guarantee: all products are strictly tested by our QC, confirmed by our QA before shipment; 3) Samples available for testing; 4) OEM/ODM Available; 5) Reasonable & Competitive price; 6) Fast

    Xi'an HDM Biotech Co., Ltd. was established in 2012. It is a high-tech professional and technical enterprise integrating R & D, production and sales. Located in the world-famous hi

  •  Xi'an HDM Biotech Co., Ltd.

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86 -029-19991242181

    Address:No. 1803, 18 / F, Unit 2, Building 1, No. 6299, Lanchi Second Road East, Zhengyang Street, Qinhan New City, Xixian New District, Shaanxi Province

       Inquiry Now

  • High quality Nadifloxacin

  • Casno:

    124858-35-1

    High quality Nadifloxacin

    Min.Order: 10 Gram

    FOB Price:  USD $ 0.0-0.0

    Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

    Hangyu Biotech is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and O

  •  Zibo Hangyu Biotechnology Development Co., Ltd

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-15965530500

    Address:Room1701, Tianxing Building,Licheng district, jinan, Shandong, China

       Inquiry Now

  • Nadifloxacin

  • Casno:

    124858-35-1

    Nadifloxacin

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0

    We offer you: 1.Top quality: Using high quality material and establishing a strict quality control system,assigning specific persons in charge of each part of production,from raw material purchase to assembly. 2 Professional R&D Team: Employed

    Our company has a number of sales team, service and information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to

  •  Qiaoxi District Yitlan electronic business Firm

    China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86-190-33111208

    Address:Hebei shijiazhuang

       Inquiry Now

  • Nadifloxacin

  • Casno:

    124858-35-1

    Nadifloxacin

    Min.Order: 10 Gram

    FOB Price:  USD $ 0.0-0.0

    Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

    TaiChem was established in 2015 and registered in China medical city - Taizhou, Jiangsu Province. The company has about 1800 square meters of class A plant facility. TaiChem focuse

  •  TaiChem Taizhou Limited

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-0523-86810091

    Address:Changjiang Dadao 18

       Inquiry Now

  • Nadifloxacin

  • Casno:

    124858-35-1

    Nadifloxacin

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0

    Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

    Zibo Dorne chemical technology co., LTD. is a biotechnology enterprise engaged in the R&D, production and sales of drugs, steroids, peptides, raw materials, vitamins, food additive

  •  Zibo Dorne chemical technology co. LTD

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-18560316533

    Address:No. 416, 4th floor, zhongguancun science and technology city, no. 1, west 6th road, zhangdian district

       Inquiry Now

  • Nadifloxacin

  • Casno:

    124858-35-1

    Nadifloxacin

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0

    Nadifloxacin Basic information Abstract Acne Treatment Antibacterial Activity Pharmacokinetics Drug resistance Application References Product Name: Nadifloxacin Synonyms: NDFX;Nadifiloxacin;NadifloxacinAPI;7-fluoro-8-(4-hydroxypiperidin-1-yl)-

    SHANGHAI MINSTAR CHEMICAL CO., LTD. is a leading, experienced, professional supplier of API & intermediates, plant extract, food additive, fine chemicals and industry chemicals, et

  •  Shanghai Minstar Chemical Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:0086-21-18019205509

    Address:BUILDING 8, NO.1098, CHUANSHA ROAD, SHANGHAI, CHINA

       Inquiry Now

  • Lower Price Nadifloxacin

  • Casno:

    124858-35-1

    Lower Price Nadifloxacin

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0

    Product name: Nadifloxacin CAS No.:124858-35-1 Molecule Formula:C19H21FN2O4 Molecule Weight:360.38 Purity: 99.0% Package: 25kg/drum Description:White powder Manufacture Standards:Enterprise Standard TESTING ITEMS

    Siwei Development Group Ltd. is a reputed professional enterprise in China dedicated to the Amino Acids production and sales of fine chemical products.Over the years we have been m

  •  Siwei Development Group Ltd.

    China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86-571-82881840

    Address:Rm2-2-503 Zhongdingyuan, Xianghurenjia Wenyan Xiaoshan, Hangzhou China

       Inquiry Now

  • Nadifloxacin

  • Casno:

    124858-35-1

    Nadifloxacin

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0

    Hangzhou ZeErRui Chemical Co., Ltd. located in Lingang industrial areas, our plant covers an area of 6000 square meters.ZeErRui dedicated to the development, production and marketing of chemicals. We have earned ourselves a good reputation at home an

    Hangzhou ZeErRui Chemical Co., Ltd. located in Lingang industrial areas, our plant covers an area of 6000 square meters.ZeErRui dedicated to the development, production and marketi

  •  Hangzhou ZeErRui Chemical Co., Ltd.

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-571-82512721

    Address:No 317,Jingling Road,Guali Town,Xiaoshan District

       Inquiry Now

  • Nadifloxacin

  • Casno:

    124858-35-1

    Nadifloxacin

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0

    Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

    Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, s

  •  Shandong Mopai Biotechnology Co., LTD

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-15965530500

    Address:shandong

       Inquiry Now

  • TIANFUCHEM--124858-35-1---Nadifloxacin

  • Casno:

    124858-35-1

    TIANFUCHEM--124858-35-1---Nadifloxacin

    Min.Order: 1 Metric Ton

    FOB Price:  USD $ 1.5-1.5

    1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

    KAISA GROUP INC.is the enterprise which is specialize in manfacturing and exporting avariety of Chemical in China. We have the strong economic base and comprehensive technology.We

  •  KAISA GROUP INC

    United States  |  Contact Details

    Business Type:Trading Company

    Tel:15131197030

    Address:1312 17th Street Suite 1402 Denver CO 80202

       Inquiry Now

  • Nadifloxacin

  • Casno:

    124858-35-1

    Nadifloxacin

    Min.Order: 100 Gram

    FOB Price:  USD $ 0.0-0.0

    Wuhu Nuovo Chemical Technology Co., Ltd. was established in August 2014, mainly engaged in the development, production and sales of ionic liquids, ribose, nucleosides, nucleotides and related chemicals; Products are mainly used in new energy, new ma

  •  Wuhu Nuowei Chemistry Technologies Co., Ltd.

    China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:86-0553-8233716

    Address:Xingduhui Block C,Huangshan East Road, Jinghu Zone

       Inquiry Now

  • Nadifloxacin

  • Casno:

    124858-35-1

    Nadifloxacin

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

    Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns

  •  Hunan chemfish Pharmaceutical co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:0731-85567275

    Address:No.10048, xiangjiang centry bulding ,kaifu district ,changsha city ,Hunan

       Inquiry Now

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 124858-35-1

Standards and Recommendations

Following a single topical application of 10gm nadifloxacin 1% cream to normal human back skin, the highest plasma concentration was determined to be 107ng./ml with an elimination half-life of 19.4 hours. Approximately 0.09% of the administered dose was excreted in the urine over 48 hours post- dosing. The plasma concentration reached a steady state on Day 5 of repeated administration study when nadifloxacin 1% cream was applied at 5 gm twice daily to normal healthy individuals for a period of 7 days. The plasma concentration reached a peak of 4.1 ng/ml at 8 hours post-final dosing with an elimination half-Life of 23.2 hours. The urinary excretion rate reached 0.16% on Day 7.

Specification

The Nadifloxacin, with the CAS registry number 124858-35-1, is also known as 1H,5H-Benzo[ij]quinolizine-2-carboxylic acid, 9-fluoro-6,7-dihydro-8-(4-hydroxy-1-piperidinyl)-5-methyl-1-oxo-, (±)-. It belongs to the product categories of Intermediates & Fine Chemicals; Pharmaceuticals. This chemical's molecular formula is C19H21FN2O4 and molecular weight is 360.38. What's more, its systematic name is 9-Fluoro-8-(4-hydroxy-1-piperidinyl)-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid. This chemical is a topical fluoroquinolone antibiotic for the treatment of acne vulgaris. It is also used to treat bacterial skin infections.

Physical properties of Nadifloxacin are: (1)ACD/LogP: 2.491; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.25; (4)ACD/LogD (pH 7.4): 0.71; (5)ACD/BCF (pH 5.5): 26.17; (6)ACD/BCF (pH 7.4): 1.00; (7)ACD/KOC (pH 5.5): 306.78; (8)ACD/KOC (pH 7.4): 8.90; (9)#H bond acceptors: 6; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 3; (12)Polar Surface Area: 81.08 Å2; (13)Index of Refraction: 1.669; (14)Molar Refractivity: 91.62 cm3; (15)Molar Volume: 245.686 cm3; (16)Polarizability: 36.321×10-24cm3; (17)Surface Tension: 71.7 dyne/cm; (18)Density: 1.467 g/cm3; (19)Flash Point: 331.722 °C; (20)Enthalpy of Vaporization: 97.264 kJ/mol; (21)Boiling Point: 624.891 °C at 760 mmHg; (22)Vapour Pressure: 0 mmHg at 25°C.

You can still convert the following datas into molecular structure:
(1)SMILES: O=C(O)\C2=C\N4c1c(c(c(F)cc1C2=O)N3CCC(O)CC3)CCC4C
(2)Std. InChI: InChI=1S/C19H21FN2O4/c1-10-2-3-12-16-13(18(24)14(19(25)26)9-22(10)16)8-15(20)17(12)21-6-4-11(23)5-7-21/h8-11,23H,2-7H2,1H3,(H,25,26)
(3)Std. InChIKey: JYJTVFIEFKZWCJ-UHFFFAOYSA-N