CAS No.13254-33-6,Carpronium chloride Suppliers

Products Categories

Pharmaceutical (58)
Organic Chemicals (7)
Others (3)
Basic Inorganic Chemicals (2)
Reagent (1)

Basic Information

Molecular Structure:
CAS No.:	13254-33-6
Name:	Carpronium chloride

Formula:	C₈H₁₈NO₂^.Cl
Molecular Weight:	195.689
Synonyms:	(3-Carboxypropyl)trimethylammoniumchloride, methyl ester (6CI,7CI);1-Butanaminium, 4-methoxy-N,N,N-trimethyl-4-oxo-,chloride (9CI);Ammonium, (3-carboxypropyl)trimethyl-, chloride, methyl ester(8CI);3-Carboxy-N,N,N-trimethyl-1-propanaminium chloride methyl ester;Actinamin;Carpronium chloride;Furozin;Methyl N-trimethyl-g-aminobutyrate chloride;Methyltrimethyl-g-aminobutyrate chloride;g-Butyrobetaine chloride methylester;
EINECS:	236-243-6
Melting Point:	126°
PSA:	26.30000
LogP:	-2.35020

Synthetic route

4-trimethylammonio-buten-(2)-oic acid (1)-methyl ester chloride: 4-trimethylammonio-buten-(2)-oic acid (1)-methyl ester chloride

: 13254-33-6
(3-carboxypropyl)trimethylammonium chloride methyl ester

Conditions

Conditions	Yield
With hydrogenchloride; palladium Hydrogenation;

: 67-56-1
methanol

4-trimethylammonio-butyric acid-chloride: 4-trimethylammonio-butyric acid-chloride

: 13254-33-6
(3-carboxypropyl)trimethylammonium chloride methyl ester

Conditions

Conditions	Yield
With hydrogenchloride

: 13254-33-6
(3-carboxypropyl)trimethylammonium chloride methyl ester

A: 96-48-0
4-butanolide

B: 75-57-0
tetramethlyammonium chloride

Conditions

Conditions	Yield
at 0 - 250℃; Mechanism; Heating; pyrolysis of various carpronium chloride derivatives, labelled derivatives;

: 1310-58-3
potassium hydroxide

: 13254-33-6
(3-carboxypropyl)trimethylammonium chloride methyl ester

: C7H15NO2*HO(1-)*K(1+)

Conditions

Conditions	Yield
In ethanol at 2 - 23℃; for 0.5 - 4h; Product distribution / selectivity;

: 1310-73-2
sodium hydroxide

: 13254-33-6
(3-carboxypropyl)trimethylammonium chloride methyl ester

: C7H15NO2*HO(1-)*Na(1+)

Conditions

Conditions	Yield
In ethanol at 2 - 23℃; for 1.5 - 4h; Product distribution / selectivity;

Total:66 Page 1 of 2 1 2 Next>>

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 13254-33-6

Specification

The Carpronium chloride ,its cas register number is 13254-33-6.It also can be called as 4-Methoxy-N,N,N-trimethyl-4-oxo-1-butanaminium chloride and the IUPAC name about this chemicals is (4-Methoxy-4-oxobutyl)-trimethylazanium chloride .This chemical has a related registry number is 14075-13-9 (Parent) .Classification code about it is Drug / Therapeutic . It is a hair growth reagent with a vasodilatory action.

The Carpronium chloride , a hair growth reagent, is known to have a vasodilatory action, but its direct effect on the microcirculation has been known very primitively. This study was aimed to examine its effects on the vascular smooth muscles and blood flow in rat mesenteric arterioles using intravital videomicroscopy. After topically applying carpronium chloride on the microvasculature, we measured changes of diameter and blood flow in the arterioles. During its topical application, arteriolar vasodilation and flow increase were observed, while no change occurred in the mean systemic blood pressure. Our in vivo studies indicated that carpronium chloride achieved dilatation of vascular smooth muscle in the microcirculation.

This chemicals can be described computed from structure:
(1)Canonical SMILES: C[N+](C)(C)CCCC(=O)OC.[Cl-]
(2)InChI: InChI=1S/C8H18NO2.ClH/c1-9(2,3)7-5-6-8(10)11-4;/h5-7H2,1-4H3;1H/q+1;/p-1
(3)InChIKey: RZMKWKZIJJNSLQ-UHFFFAOYSA-M

The most important thing about Carpronium chloride is the toxicity, following is the form:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Source
mouse	LD50	intraperitoneal	14600ug/kg (14.6mg/kg)	Oyo Yakuri. Pharmacometrics. Vol. 1, Pg. 74, 1967.
mouse	LD50	oral	134mg/kg (134mg/kg)	Drugs in Japan Vol. 6, Pg. 135, 1982.
mouse	LD50	skin	> 520mg/kg (520mg/kg)	Drugs in Japan Vol. -, Pg. 283, 1990.
rat	LD50	oral	478mg/kg (478mg/kg)	Drugs in Japan Vol. 6, Pg. 135, 1982.
rat	LD50	skin	8484mg/kg (8484mg/kg)	Drugs in Japan Vol. -, Pg. 283, 1990.