Products Categories
CAS No.: | 1435-49-0 |
---|---|
Name: | 1,2-Dichloro-4-fluorobenzene |
Article Data: | 11 |
Molecular Structure: | |
Formula: | C6H3Cl2F |
Molecular Weight: | 164.994 |
Synonyms: | 1-Fluoro-3,4-dichlorobenzene;3,4-Dichloro-1-fluorobenzene;3,4-Dichlorofluorobenzene;NSC 82300; |
EINECS: | 215-858-3 |
Density: | 1.403 g/cm3 |
Melting Point: | -1 °C(lit.) |
Boiling Point: | 172.2 °C at 760 mmHg |
Flash Point: | 64.4 °C |
Appearance: | clear colorless to slightly yellow liquid |
Hazard Symbols: | Xi; Xn |
Risk Codes: | 22-36/37/38 |
Safety: | 26-37/39 |
Transport Information: | UN 1993 |
PSA: | 0.00000 |
LogP: | 3.13250 |
3,4-dichlorofluorobenzene
Conditions | Yield |
---|---|
With lithium hydroxide monohydrate; silver trifluoromethanesulfonate; Selectfluor In ethyl acetate at 55℃; Sealed tube; | 75% |
4-bromo-1,2-dichlorobenzene
3,4-dichlorofluorobenzene
Conditions | Yield |
---|---|
Stage #1: 4-bromo-1,2-dichlorobenzene With TurboGrignard In tetrahydrofuran; 1,4-dioxane at 0 - 25℃; Inert atmosphere; Stage #2: With N-fluorobis(benzenesulfon)imide In dichloromethane; octadecafluorodecahydronaphthalene (cis+trans) at -78 - 20℃; Inert atmosphere; | 34% |
Stage #1: 4-bromo-1,2-dichlorobenzene With TurboGrignard In tetrahydrofuran at 0℃; Inert atmosphere; Stage #2: With N-fluorobis(benzenesulfon)imide In dichloromethane; octadecafluorodecahydronaphthalene (cis+trans) at -78 - 25℃; Inert atmosphere; | 34% |
Conditions | Yield |
---|---|
Reaktion nach Sandmeyer; |
Conditions | Yield |
---|---|
With hydrogenchloride; tetrafluoroboric acid; sodium nitrite Erhitzen des Reaktionsprodukts auf 150grad; |
2,3-dichlorofluorobenzene
A
3,4-dichlorofluorobenzene
B
3-chlorofluorobenzene
C
1,4-dichloro-2-fluorobenzene
D
1,3-dichloro-4-fluorobenzene
Conditions | Yield |
---|---|
In acetonitrile for 10h; Product distribution; Irradiation; | A 5 % Chromat. B 5 % Chromat. C 13 % Chromat. D 1 % Chromat. |
sulfuric acid
m,p-dichloroaniline
A
3,4-dichlorofluorobenzene
B
3,4-dichlorophenol
C
1,2-dichloro-benzene
Conditions | Yield |
---|---|
Behandeln der Diazoloesung mit heisser Flusssaeure.Diazotization; |
fluorobenzene
A
3,4-dichlorofluorobenzene
B
1-Chloro-4-fluorobenzene
C
1,3-dichloro-4-fluorobenzene
Conditions | Yield |
---|---|
Einleiten von 2 Mol Chlor; |
3,4-dichlorofluorobenzene
3,4-dichlorofluorobenzene
Conditions | Yield |
---|---|
With tetrakis(acetonitrile)copper(I)tetrafluoroborate; [4,4’-bis(1,1-dimethylethyl)-2,2’-bipyridine-N1,N1‘]bis [3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-N]phenyl-C]iridium(III) hexafluorophosphate; cesium fluoride In acetone at 30℃; for 20h; Inert atmosphere; Irradiation; | 63 %Spectr. |
3,4-dichlorofluorobenzene
N,N-dimethyl-formamide
2,3-Dichloro-6-fluorobenzaldehyde
Conditions | Yield |
---|---|
Stage #1: 3,4-dichlorofluorobenzene With lithium diisopropyl amide In tetrahydrofuran at -65℃; for 0.5h; Inert atmosphere; Stage #2: N,N-dimethyl-formamide In tetrahydrofuran at -65℃; for 0.333333h; Inert atmosphere; | 94% |
What can I do for you?
Get Best Price
The Benzene,1,2-dichloro-4-fluoro-, with CAS registry number 1435-49-0, belongs to the following product categories: (1)Chlorine Compounds; (2)Fluorine Compounds. It has the systematic name of 1,2-dichloro-4-fluorobenzene. This chemical is a kind of clear colorless to slightly yellow liquid. The main use of this chemical is for the intermediate of pesticide, medicine and liquid crystal material.
Physical properties of Benzene,1,2-dichloro-4-fluoro-: (1)ACD/LogP: 2.84; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.84; (4)ACD/LogD (pH 7.4): 2.84; (5)ACD/BCF (pH 5.5): 85.36; (6)ACD/BCF (pH 7.4): 85.36; (7)ACD/KOC (pH 5.5): 839.47; (8)ACD/KOC (pH 7.4): 839.47; (9)#H bond acceptors: 0; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 0; (12)Polar Surface Area: 0 Å2; (13)Index of Refraction: 1.525; (14)Molar Refractivity: 36.03 cm3; (15)Molar Volume: 117.5 cm3; (16)Polarizability: 14.28×10-24cm3; (17)Surface Tension: 35.1 dyne/cm; (18)Enthalpy of Vaporization: 39.18 kJ/mol; (19)Vapour Pressure: 1.79 mmHg at 25°C.
When you are using this chemical, please be cautious about it as the following:
The Benzene,1,2-dichloro-4-fluoro- irritates to eyes, respiratory system and skin. And this chemical is harmful if swallowed. When use it, wear suitable protective clothing, gloves and eye/face protection. If contact with eyes, rinse immediately with plenty of water and seek medical advice.
You can still convert the following datas into molecular structure:
(1)SMILES: Fc1cc(Cl)c(Cl)cc1
(2)InChI: InChI=1/C6H3Cl2F/c7-5-2-1-4(9)3-6(5)8/h1-3H
(3)InChIKey: QSDKXMVGRLVIQV-UHFFFAOYAG
(4)Std. InChI: InChI=1S/C6H3Cl2F/c7-5-2-1-4(9)3-6(5)8/h1-3H
(5)Std. InChIKey: QSDKXMVGRLVIQV-UHFFFAOYSA-N