CAS No.14899-36-6,Dexamethasone palmitate Suppliers

Products Categories

Pharmaceutical (75)
Organic Chemicals (8)
Others (5)
Reagent (1)

Basic Information

Molecular Structure:
CAS No.:	14899-36-6
Name:	Dexamethasone palmitate
Article Data:	1

Formula:	C38H59 F O6
Molecular Weight:	630.881
Synonyms:	Pregna-1,4-diene-3,20-dione,9-fluoro-11b,17,21-trihydroxy-16a-methyl-, 21-palmitate (6CI,8CI);Palmitic acid, 21-ester with 9-fluoro-11b,17,21-trihydroxy-16a-methylpregna-1,4-diene-3,20-dione (8CI);Dexamethasone 21-palmitate; Dexamethasone palmitate; Limethason; Limethasone;Lipotalon
Density:	1.12
Melting Point:	60-65 °C
Boiling Point:	710.1°Cat760mmHg
Flash Point:	383.2°C
Safety:	An experimental teratogen. Other experimental reproductive effects. A steroid. When heated to decomposition it emits toxic fumes of F⁻.
PSA:	100.90000
LogP:	7.92790

Synthetic route

: 112-39-0
hexadecanoic acid methyl ester

: 50-02-2
dexamethasone

: 14899-36-6
dexamethasone palmitate

Conditions

Conditions	Yield
With ceria-doped alumina at 40 - 80℃; under 525.053 Torr; for 3h; Reagent/catalyst; Pressure; Temperature; Inert atmosphere;	92%

: 14899-36-6
dexamethasone palmitate

human low density protein: human low density protein

oxidized dexamethasone palmitate-human low density lipoprotein complex: oxidized dexamethasone palmitate-human low density lipoprotein complex

Conditions

Conditions	Yield
Stage #1: dexamethasone palmitate; human low density protein With Celite at 37℃; for 20h; Complex formation; Stage #2: With copper(II) sulfate at 37℃; for 20h; Oxidation;

Total:77 Page 1 of 3 1 2 3 Next>>

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 14899-36-6

Chemistry

Molecule structure of Dexamethasone palmitate (CAS NO.14899-36-6):

IUPAC Name: [2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-Fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] hexadecanoate
Molecular Weight: 630.869863 g/mol
Molecular Formula: C₃₈H₅₉FO₆
Density: 1.12 g/cm³
Melting Point: 60-65 °C
Boiling Point: 710.1 °C at 760 mmHg
Flash Point: 383.2 °C
Index of Refraction: 1.537
Molar Refractivity: 174.65 cm³
Molar Volume: 558.9 cm³
Polarizability: 69.23×10^-24 cm³
Surface Tension: 46.7 dyne/cm
Enthalpy of Vaporization: 118.65 kJ/mol
Vapour Pressure: 2.69E-23 mmHg at 25 °C
XLogP3: 9.8
H-Bond Donor: 2
H-Bond Acceptor: 7
Rotatable Bond Count: 18
Tautomer Count: 6
Exact Mass: 630.429568
MonoIsotopic Mass: 630.429568
Topological Polar Surface Area: 101
Heavy Atom Count: 45
Complexity: 1130
Defined Atom StereoCenter Count: 8
Canonical SMILES: CCCCCCCCCCCCCCCC(=O)OCC(=O)C1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)F))C)C)O
Isomeric SMILES: CCCCCCCCCCCCCCCC(=O)OCC(=O)[C@]1([C@@H](C[C@@H]2[C@@]1(C[C@@H][C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)O)C)C)O
InChI: InChI=1S/C38H59FO6/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-34(43)45-26-33(42)38(44)27(2)23-31-30-20-19-28-24-29(40)21-22-35(28,3)37(30,39)32(41)25-36(31,38)4/h21-22,24,27,30-32,41,44H,5-20,23,25-26H2,
1-4H3/t27-,30+,31+,32+,35+,36+,37+,38+/m1/s1
InChIKey: WDPYZTKOEFDTCU-WDJQFAPHSA-N
Classification Code of Dexamethasone palmitate (CAS NO.14899-36-6): Drug / Therapeutic Agent; Hormone; Reproductive Effect

Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intravenous	> 160mg/kg (160mg/kg)	GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" GASTROINTESTINAL: NAUSEA OR VOMITING LIVER: OTHER CHANGES	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 3998, 1985.
mouse	LD50	intravenous	300mg/kg (300mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 544, 1988.
mouse	LD50	oral	510mg/kg (510mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 544, 1988.
mouse	LD50	subcutaneous	120mg/kg (120mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 544, 1988.
rat	LD50	intravenous	88mg/kg (88mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 544, 1988.
rat	LD50	oral	315mg/kg (315mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 544, 1988.
rat	LD50	subcutaneous	90mg/kg (90mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 544, 1988.

Safety Profile

An experimental teratogen. Other experimental reproductive effects. A steroid. When heated to decomposition it emits toxic fumes of F⁻.

Specification

Dexamethasone palmitate (CAS NO.14899-36-6) is also named as 9-Fluoro-11,17-dihydroxy-16-methyl-21-((1-oxohexadecyl)oxy)pregna-1,4-diene-3,20-dione (11beta,16alpha)- ; BRN 6031847 ; Dexamethasone 21-palmitate ; Limethason ; Palmitic acid, 21-ester with 9-fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione ; Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-((1-oxohexadecyl)oxy)-, (11beta,16alpha)- ; Pregna-1,4-diene-3,20-dione, 9-fluoro-11-beta,17,21-trihydroxy-16-alpha-methyl-, 21-palmitate .