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15679-12-6

Basic Information
CAS No.: 15679-12-6
Name: 2-Ethyl-4-methyl thiazole
Article Data: 9
Molecular Structure:
Molecular Structure of 15679-12-6 (2-Ethyl-4-methyl thiazole)
Formula: C6H9NS
Molecular Weight: 127.21
Synonyms: 2-Ethyl-4-methylthiazole;
EINECS: 239-757-9
Density: 1.049 g/cm3
Boiling Point: 173.3 °C at 760 mmHg
Flash Point: 54.4 °C
Appearance: clear colorless or pale yellow to light brown liquid
Hazard Symbols: IrritantXi
Risk Codes: 10
Safety: 16-26-36
Transport Information: UN 1993 3/PG 3
PSA: 41.13000
LogP: 2.01390
Synthetic route
45534-10-9

2-ethenyl-4-methyl-1,3-thiazole

15679-12-6

2-ethyl-4-methyl-1,3-thiazole

Conditions
ConditionsYield
Hydrogenation;
41803-21-8

2-ethyl-4-methyl-3-thiazoline

15679-12-6

2-ethyl-4-methyl-1,3-thiazole

Conditions
ConditionsYield
With ethanol; iron(III) chloride
With sulfur
7533-07-5

1-(4-methyl-1,3-thiazol-2-yl)ethan-1-one

15679-12-6

2-ethyl-4-methyl-1,3-thiazole

631-58-3

thiopropanamide

78-95-5

chloroacetone

15679-12-6

2-ethyl-4-methyl-1,3-thiazole

Conditions
ConditionsYield
With ethanol
541-58-2

2,4-dimethylthiazole

80-48-8

methyl p-toluene sulfonate

A

15679-12-6

2-ethyl-4-methyl-1,3-thiazole

B

13623-11-5

2,4,5-trimethylthiazole

Conditions
ConditionsYield
(i) nBuLi, Et2O, (ii) /BRN= 609209/; Multistep reaction;
802294-64-0

propionic acid

78-95-5

chloroacetone

15679-12-6

2-ethyl-4-methyl-1,3-thiazole

Conditions
ConditionsYield
Stage #1: propionic acid With dmap; dacarbazine; Rink resin Acylation; amidation;
Stage #2: With Lawessons reagent In tetrahydrofuran for 4h; thioamidation; Heating;
Stage #3: chloroacetone In tetrahydrofuran for 16h; Cyclization; Heating;
333385-00-5

methylhydroxyethyl thiazole

15679-12-6

2-ethyl-4-methyl-1,3-thiazole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: KOH / 200 °C
2: Hydrogenation
View Scheme
15679-12-6

2-ethyl-4-methyl-1,3-thiazole

573-17-1

9-bromophenanthrene

2-ethyl-4-methyl-5-(phenanthren-9-yl)thiazole

Conditions
ConditionsYield
With potassium acetate; palladium diacetate In N,N-dimethyl acetamide at 150℃; for 16h; Inert atmosphere; Schlenk technique;97%
15679-12-6

2-ethyl-4-methyl-1,3-thiazole

10342-83-3

4'-Bromopropiophenone

1-(4-(2-ethyl-4-methylthiazol-5-yl)phenyl)propan-1-one

Conditions
ConditionsYield
With palladium 10% on activated carbon; potassium acetate In i-Amyl alcohol at 150℃; for 16h; Solvent; Inert atmosphere; Green chemistry;96%
15679-12-6

2-ethyl-4-methyl-1,3-thiazole

623-00-7

4-bromobenzenecarbonitrile

4-(2-ethyl-4-methylthiazol-5-yl)benzonitrile

Conditions
ConditionsYield
With palladium 10% on activated carbon; potassium acetate In i-Amyl alcohol at 150℃; for 16h; Solvent; Inert atmosphere; Green chemistry;96%
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  • 2-Ethyl-4-methyl thiazole

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    15679-12-6

    2-Ethyl-4-methyl thiazole

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  • SAGECHEM/  2-Ethyl-4-methyl thiazole /Manufacturer in China

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  • Thiazole,2-ethyl-4-methyl-

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    15679-12-6

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  • 2-Ethyl-4-methylthiazole CAS 15679-12-6

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  • 2-Ethyl-4-methylthiazole CAS 15679-12-6

  • Casno:

    15679-12-6

    2-Ethyl-4-methylthiazole CAS 15679-12-6

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    Name: 2-Ethyl-4-methylthiazole CAS: 15679-12-6 Molecular Formula: C6H9NS Molecular Weight: 127.207 Application:Fine chemical

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  • 2-Ethyl-4-Methylthiazole

  • Casno:

    15679-12-6

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  • Thiazole,2-ethyl-4-methyl-

  • Casno:

    15679-12-6

    Thiazole,2-ethyl-4-methyl-

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  • 2-Ethyl-4-Methylthiazole

  • Casno:

    15679-12-6

    2-Ethyl-4-Methylthiazole

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

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Chemistry

Molecular Formula: C6H9NS
Formula Weight: 127.21
bp of 2-ethyl-4-methylthiazole (15679-12-6): 161-162 °C(lit.)
density : 1.026 g/mL at 25 °C(lit.)
refractive index : n20/D 1.505(lit.)
FEMA : 3680
Fp of 2-ethyl-4-methylthiazole (15679-12-6): 130 °F
Physical State: clear to pale yellow liquid
Odor of 2-ethyl-4-methylthiazole (15679-12-6): stench

Uses

2-ethyl-4-methylthiazole (15679-12-6) is used as thiol flavouring substances, also is used in flavorings (coffee, cocoa, nutty).

Toxicity Data With Reference

LD50/LC50: Not available.
Carcinogenicity: 2-ethyl-4-methylthiazole (15679-12-6) - Not listed by ACGIH, IARC, or NTP.

Safety Profile

Hazard Codes : Xi (Irritant)
Risk Statements : 10-36/37/38 (Flammable; Irritating to eyes, respiratory system and skin)
Safety Statements : 16-26-36 (Keep away from sources of ignition - No smoking; In case of contact with eyes, rinse immediately with plenty of water and seek medical advice; Wear suitable protective clothing)
RIDADR : UN 1993 3/PG 3
WGK Germany : 3
Hazard Note : Irritant
HazardClass : 3
PackingGroup : III

Standards and Recommendations

ASSAY: 99.0% min
SPECIFIC GRAVITY: 1.02-1.03

Specification

Storage of 2-ethyl-4-methylthiazole (15679-12-6): Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from sources of ignition. Keep away from heat, sparks, and flame. Flammables-area.