Detail of "1888-91-1"

Reference

Purity monitoring of the preparation Acemin by chromatography on Silufol plates

Purity monitoring of the preparation Acemin by chromatography on Silufol plates. Georgievskii, V. P.; Khovanskaya, N. P.; Mikhailova, I. Yu.; Muratova, T. L. (All-Union Res. Inst. Chem. Technol. Drugs, USSR). Farm. Zh. (Kiev), (6), 35-7 (Ukrainian) 1983. CODEN: FRZKAP. ISSN: 0367-3057. DOCUMENT TYPE: Journal CA Section: 64 (Pharmaceutical Analysis) Acemin[AcNH(CH2)5CO2H] [57-08-9] (a wound-curing prepn.) was analyzed for possible impurities (caprolactam [105-60-2], acetylcaprolactam [1888-91-1], and aminocaproic acid [1319-82-0]) using ascending TLC on Silutol plates. Caprolactam and acetylcaprolactam were detd. with Me2CO, salicylal + maleic acid developer, and detection at 365 nm. Aminocaproic acid was detd. using PrOH-H2O (7:3) solvent and ninhydrin in BuOH for development. The detection limits were 0.2, 0.2, and 0.5 mg for caprolactam, acetylcaprolactam, and aminocaproic acid, resp.

Effect of the nature of the activator on the kinetics of anionic activated polymerization of a-pyrrolidinone

Effect of the nature of the activator on the kinetics of anionic activated polymerization of a-pyrrolidinone. Vasil'iev, N. I.In this study， 89519-24-4 and 616-45-5 are also used.; Kholodenko, B. V.; Andrianova, G. P. (Nauchno-Proizvod. Ob'edin. "Plastmassy", USSR). Vysokomol. Soedin., Ser. B, 26(1), 72-5 (Russian) 1984. CODEN: VYSBAI. ISSN: 0507-5483. DOCUMENT TYPE: Journal CA Section: 35 (Chemistry of Synthetic High Polymers) The rates of polymn. of a-pyrrolidinone [616-45-5] catalyzed by a-pyrrolidinone sodium salt [3195-95-7] were nearly the same in the presence of activators N-acetylpyrrolidinone (I) [932-17-2] or 4-acetylcaprolactam (II) [1888-91-1]. The activator e-caprolactone [502-44-3] accelerated the polymn. rate in the initial stages of the reaction relative to the rates in the presence of I or II, and the polymn. rates in the presence of chlorotripyrrolidinonylstannane [89519-23-3] or chlorotripyrrolidinonylsilane [89519-24-4] were substantially slower than in the presence of I or II. Lower activity of the Sn- and Si-contg. activators than that of I and II was attributed to lower nucleophilicity of macroanions contg. SnCl and SiCl groups and, consequently, slower rates of H+ transfer from the monomer to the macroanions giving the monomer anion subsequently participating in chain propagation. .