299-42-3

Molecular Structure:

Molecular Formula: C₁₀H₁₅NO
Molecular Weight: 165.2322
IUPAC Name: (1R,2S)-2-(Methylamino)-1-phenylpropan-1-ol
Synonyms of Ephedrine (CAS NO.299-42-3): (-)-Ephedrine ; (-)-alpha-(1-Methylaminoethyl)benzyl alcohol ; 1-2-Methylamino-1-phenylpropanol ; 1-Hydroxy-2-methylamino-1-phenylpropane ; 1-Phenyl-1-hydroxy-2-methylaminopropane ; 1-Phenyl-2-methylaminopropanol ; 1-Sedrin ; 1-alpha-(1-Methylaminoethyl)benzyl alcohol ; 2-Methylamino-1-phenyl-1-propanol ; AI3-02761 ; Benzenemethanol, alpha-(1-(methylamino)ethyl)-, (R-(R*,S*))- ; Biophedrin ; EINECS 206-080-5 ; Eciphin ; Efedrin ; Ephedral ; Ephedremal ; Ephedrin ; Fedrin ; HSDB 3072 ; I-Sedrin ; Kratedyn ; L(-)-Ephedrine ; Lexofedrin ; Manadrin ; Mandrin ; NCI-C55652 ; NSC 170951 ; NSC 8971 ; Nasol ; Norephedrine, N-methyl- ; Sanedrine ; UNII-GN83C131XS ; Vencipon ; Zephrol ; alpha-(1-(Methylamino)ethyl)benzenemethanol ; alpha-Hydroxy-beta-methyl amine propylbenzene ; alpha-Hydroxy-beta-methylaminopropylbenzene ; i-Sedrin ; l-2-Methylamino-1-phenylpropanol ; l-Ephedrine ; l-alpha-(1-Methylaminoethyl)benzyl alcohol
CAS NO: 76-05-1
Classification Code: Adrenergic agents ; Autonomic Agents ; Bronchodilator ; Cardiovascular Agents ; Central Nervous System Agents ; Central nervous system stimulants ; Drug / Therapeutic Agent ; Human Data ; Natural Product ; Neurotransmitter Agents ; Peripheral Nervous System Agents ; Reproductive Effect ; Sympathomimetics ; Vasoconstrictor agents
Melting point: 37-39 °C
Index of Refraction: 1.528
Molar Refractivity: 50.15 cm³
Molar Volume: 162.7 cm³
Surface Tension: 38 dyne/cm
Density: 1.015 g/cm³
Flash Point: 85.6 °C
Enthalpy of Vaporization: 52.03 kJ/mol
Boiling Point: 255 °C at 760 mmHg
Vapour Pressure: 0.00865 mmHg at 25°C

1. Optically pure amines used as resolving agents include alkaloids such as ephedrine. Medication.
2. In traditional Chinese medicine, ephedrine has been used in the treatment of asthma and bronchitis for centuries.
As a sympathomimetic agent similar in structure and activity to amphetamines, there has been a dispute over whether ephedrine produces any neurodegenerative effects.
3. Several studies have recently compared the quantities of such neurotransmitters as serotonin, dopamine, glutamate, and epinephrine after concurrent administration of ephedrine and various amphetamine-like agents.
4. Ephedrine (CAS NO.299-42-3) increases serum dopamine levels minimally in comparison with an equivalent dose of dextroamphetamine (Dexedrine).

  Ephedrine(299-42-3) is reported in EPA TSCA Inventory.

Hazard Codes of Ephedrine (CAS NO.299-42-3): Xn
WGK Germany: 1
RTECS: KB0700000
Hazard Note: Harmful
A human poison by an unspecified route. An experimental poison by intravenous, subcutaneous, intramuscular, and intraperitoneal routes. Moderately toxic by ingestion and parenteral routes. Causes rapid pulse, rise in blood pressure, and other actions similar to epinephrine. An experimental teratogen. Used in production of drugs of abuse. Has been known to cause allergic sensitization.

Handling and Storage of Ephedrine (CAS NO.299-42-3):
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Refrigerator (approx 4 ^oC). Store protected from moisture. Store protected from light. Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Store protected from light.