Detail of "31112-62-6"

Reference

ECG changes and arrhythmias induced by ionic and non-ionic contrast media during coronary arteriography in dogs

ECG changes and arrhythmias induced by ionic and non-ionic contrast media during coronary arteriography in dogs. Tragardh, Bengt; Lynch, Peter R. (Dep. Diagn. Radiol., Malmo Gen. Hosp., Malmo, Swed.). Invest. Radiol., 13(3), 233-7 (English) 1978. CODEN: INVRAV. ISSN: 0020-9996. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Amipaque (metrizamide) [31112-62-6], Renografin 76 (diatrizoate) [8064-12-8] and isopaque 370 (metrizoate) [52627-78-8] were selectively injected into the right or the left canine coronary artery of dogs. The EKG was recorded and external defibrillation was performed whenever ventricular fibrillation occurred. During left coronary injections, metrizamide prolonged the PQ and QT intervals less than did the diatrizoate. During right coronary injections, metrizamide affected the QT interval less than either diatrizoate and metrizoate did.. During right coronary infusions, metrizamide caused fewer incidences of ventricular fibrillation than diatrizoate did. In clin. coronary arteriog., it is assumed that metrizamide would generate fewer AV blocks than diatrizoate and fewer incidences of ventricular fibrillation after right coronary injections than diatrizoate. Changes in the PQ and QT intervals during coronary arteriog. can be used as tests to predict the safety of new contrast media.

Comparison of arachnoiditis produced by meglumine locarmate and metrizamide myelography in an animal model

Comparison of arachnoiditis produced by meglumine locarmate and metrizamide myelography in an animal model. Haughton, Victor M.; Ho, Khang-Cheng; Larson, Sanford J.; Unger, George F.; Correa-Paz, Francisco (Dep. Radiol., Med. Coll. Wisconsin, Milwaukee, Wis., USA). Am. J. Roentgenol., 131(1), 129-32 (English) 1978. CODEN: AJROAM. ISSN: 0092-5381. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Section cross-reference(s): 8 Myelog. in stumptail macaques was performed with either meglumine iocarmate (I) [54605-45-7] or metrizamide (II) [31112-62-6]. After 12 wk 3 of 4 animals in the I group had severe arachnoiditis; none of the 4 animals in the II group had any severe changes in the arachnoid.