CAS No.35285-68-8,p-Hydroxybenzoic acid ethyl ester sodium salt Suppliers

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Basic Information

Molecular Structure:
CAS No.:	35285-68-8
Name:	p-Hydroxybenzoic acid ethyl ester sodium salt
Article Data:	2

Formula:	C₉H₉NaO₃
Molecular Weight:	188.158
Synonyms:	Benzoicacid, 4-hydroxy-, ethyl ester, sodium salt (9CI);4-Hydroxybenzoic acid ethyl ester sodiumsalt;E 215;Ethyl 4-hydroxybenzoate sodium salt;Ethyl p-hydroxybenzoatesodium salt;Sodium p-(carbethoxy)phenoxide;
EINECS:	252-487-6
Density:	1.34[at 20℃]
Melting Point:	>115°C(free ester)
Boiling Point:	297.5 °C at 760 mmHg
Flash Point:	120.3 °C
Solubility:	1000g/L at 23℃
PSA:	49.36000
LogP:	2.00710

Synthetic route

: 1268380-09-1
phenyl 4-ethoxycarbonyl phenyl

A: 81256-74-8
sodium salicylat

B: 35285-68-8
sodium salt of ethyl-4-hydroxybenzoate

Conditions

Conditions	Yield
With water; sodium hydroxide In dimethyl sulfoxide at 25℃; Kinetics;	A n/a B 100%

: 120-47-8
Ethyl 4-hydroxybenzoate

: 35285-68-8
sodium salt of ethyl-4-hydroxybenzoate

Conditions

Conditions	Yield
With sodium hydroxide In water
With sodium hydroxide In water

: 35285-68-8
sodium salt of ethyl-4-hydroxybenzoate

: ethyl 2-(4-carbethoxyphenoxy)-3,4-dihydrobenzoate

Conditions

Conditions	Yield
With oxygen; N,N-bis[2-(N-methylbenzimidazol-2-yl)ethyl]benzylamine; tetrakis(acetonitrile)copper(I)tetrafluoroborate In acetonitrile at 25℃; for 0.583333h; Oxidation; oxygenation; coupling;	84%

: 35285-68-8
sodium salt of ethyl-4-hydroxybenzoate

: 84942-83-6
hexakis[4-(ethoxycarbonyl)phenoxy]cyclotriphosphazene

Conditions

Conditions	Yield
With 2,2,4,4,6,6-hexachloro-1,3,5-triaza-2,4,6-triphosphorine In 1,4-dioxane at 110℃; for 72h; Inert atmosphere;	74%

: 165287-54-7
2,3-dibromo-1,4-bis-(4-bromo-phenyl)-butane-1,4-dione

: 35285-68-8
sodium salt of ethyl-4-hydroxybenzoate

: 1-(4-carboethoxyphenoxy)-1,2-bis(4-bromobenzoyl)ethylene

Conditions

Conditions	Yield
In tetrahydrofuran for 1.5h; Heating;	70%

: 3943-89-3
Ethyl protocatechuate

: 35285-68-8
sodium salt of ethyl-4-hydroxybenzoate

: ethyl 2-(4-carbethoxyphenoxy)-3,4-dihydrobenzoate

Conditions

Conditions	Yield
With sodium iodate; ethanol 1.) H2O, 25 deg C; Yield given. Multistep reaction;

: 3926-62-3
sodium monochloroacetic acid

: 35285-68-8
sodium salt of ethyl-4-hydroxybenzoate

: 30893-58-4
4-(ethoxycarbonyl)phenoxyacetic acid

Conditions

Conditions	Yield
With Amberlite IRA 400 1.) water, 2.) water, 100 deg C, 1 h; Yield given. Multistep reaction;

: 35285-68-8
sodium salt of ethyl-4-hydroxybenzoate

: 2524-03-0
dimethyl chlorothiophosphate

: 59288-80-1
O,O-Dimethyl-O-p-aethoxycarbonylphenyl-thiophosphat

Conditions

Conditions	Yield
With pyridine In toluene

: 35285-68-8
sodium salt of ethyl-4-hydroxybenzoate

: 813-77-4
Dimethyl chlorophosphate

: 59288-77-6
O,O-Dimethyl-O-p-aethoxycarbonylphenyl-phosphat

Conditions

Conditions	Yield
In benzene

: 35285-68-8
sodium salt of ethyl-4-hydroxybenzoate

: 2,5-bis(4-bromophenyl)-3-(4-carboethoxyphenoxy)furan

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 70 percent / tetrahydrofuran / 1.5 h / Heating 2: 72 percent / PCl3 / 4 h / Heating View Scheme

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Chemistry

Empirical Formula: C₉H₉NaO₃
Molecular Weight: 188.1557 g/mol
EINECS: 252-487-6
Flash Point: 120.3 °C
Enthalpy of Vaporization: 55.89 kJ/mol
Boiling Point: 297.5 °C at 760 mmHg
Vapour Pressure: 0.000759 mmHg at 25 °C
Structure of Sodium ethyl p-hydroxybenzoate (CAS NO.35285-68-8):

IUPAC Name: Sodium 4-ethoxycarbonylphenolate
Product Category of Sodium ethyl p-hydroxybenzoate (CAS NO.35285-68-8): Aromatic Esters;Benzoic acid Series

Uses

Sodium ethyl p-hydroxybenzoate (CAS NO.35285-68-8) is a water-soluble preservative. The main features is safe, efficient, and broad-spectrum antibiotic. It is widely used for anti-corrosion in the pharmaceutical industry (Chinese herbal medicine, Chinese medicine preparation agent; medical instruments sterilization); food industry (dairy products, pickled products, beverages, fruit juice, jelly, cakes, etc.); textile industry (textiles, cotton yarn, chemical fiber) . As well as others such as cosmetics', feed's, daily industrial anti-corrosion.

Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	520mg/kg (520mg/kg)	PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA	Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 45, Pg. 260, 1956.
mouse	LD50	oral	2500mg/kg (2500mg/kg)		Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 45, Pg. 260, 1956.

Specification

Sodium ethyl p-hydroxybenzoate , its cas register number is 35285-68-8. It also can be called Sodium 4-ethoxycarbonylphenoxide ; p-Hydroxybenzoic acid ethyl ester sodium salt ; and 4-Hydroxybenzoic acid, ethyl ester, sodium salt .