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Detail of "35607-66-0"

  • MSDS Download
  • CAS Number:
  • 35607-66-0
  • Name:

  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,3-[[(aminocarbonyl)oxy]methyl]-7-methoxy-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-,(6R,7S)-

  • Superlist Name:
  • Cefoxitin
  • Molecular Structure:
  • Formula:
  • C16H17N3O7S2
  • Molecular Weight:
  • 427.48
  • Synonyms:
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,3-[[(aminocarbonyl)oxy]methyl]-7-methoxy-8-oxo-7-[(2-thienylacetyl)amino]-,(6R,7S)- (9CI);5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,3-[[(aminocarbonyl)oxy]methyl]-7-methoxy-8-oxo-7-[(2-thienylacetyl)amino]-,(6R-cis)-;Cephoxitin;
  • EINECS:
  • 252-641-2
  • Density:
  • 1.63 g/cm3
  • Boiling Point:
  • 843.4 °C at 760 mmHg
  • Flash Point:
  • 463.9 °C
  • Appearance:
  • White to off-white crystalline powder
  • Transport Information:
  • UN 3077
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CAS No.35607-66-0 CefoxitinCompetitive Product

Cefoxitin

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CAS No.35607-66-0 Cefoxitin

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CAS No.35607-66-0 Cefoxitin

CEFOXITIN

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CAS No.35607-66-0 Cefoxitin

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CAS No.35607-66-0 Cefoxitin

Supplier:ChemOrganic Limited [ China (Mainland)]

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CAS No.35607-66-0 Cefoxitin

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CAS No.35607-66-0 Cefoxitin

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CAS No.35607-66-0 Cefoxitin

Assay:≥97.5%  Appearance:White to alm...  Package:5KG/TinStorage:Preserve in ...

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CAS No.35607-66-0 Cefoxitin

Molecular Formula: C16H176N3O7S2 Molecular Weight: 427.44 CAS No.: 35607-66-0 Specifications: Appearance: White to almost white powder Assay(On dry basis): ≥97.5% Specific rotation: +195°～+208° Water: ≤5.0% Total impurities: ≤4% Any individual impurity: ≤0.5% Total Re

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CAS No.35607-66-0 Cefoxitin

TOXICITY: N/A SAFETY: N/A Production: N/A Others: APIChem is a professional supplier of Research Chemicals. We have this item in stock, purity: 98%.

Supplier:Hangzhou APIChem Technology Co., Ltd. [ China (Mainland)]

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CAS No.35607-66-0 Cefoxitin

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CAS No.35607-66-0 Cefoxitin

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Reference

BL-S786, a new parenteral cephalosporin
BL-S786, a new parenteral cephalosporin. II. In vitro antimicrobial activity comparison with six related cephalosporins. Jones, R. N.; Thornsberry, C.; Barry, A. L.; Fuchs, P. C.; Gavan, T. L.; Gerlach, E. H. (Clin. Microbiol. Div., Kaiser Found. Hosp. Lab., Portland, Oreg., USA). J. Antibiot., 30(7), 583-92 (English) 1977. CODEN: JANTAJ. DOCUMENT TYPE: Journal CA Section: 3 (Biochemical Interactions) BL-S786 [60925-61-3] was compared by in vitro studies with 6 other parenteral cephalosporins (cefamandole [34444-01-4], cefazolin [25953-19-9], cefoxitin [35607-66-0], cephaloridine [50-59-9], cephalothin [153-61-7], and cephradine [38821-53-3]). BL-S786 showed the greatest antimicrobial activity against Klebsiella pneumoniae, Citrobacter diversus, and Salmonella species; was equal to cefamandole against Escherichia coli, Enterobacter agglomerans, and Proteus mirabilis; and was 2nd to cefamandole against Shigella, Edwardsiella tarda, C. freundii, Enterobacter cloacae, Enterobacter aerogenes, and the pathogenic neisseriae. Essentially no activity against Serratia and Pseudomonas species was obsd. Compared to the other cephalosporins tested, BL-S786 showed poor activity against staphylococci and streptococci. For most species tested, the min. bactericidal concns. (MBC) of the various cephalosporins was the same or within one diln. of their resp. min. inhibitory concns. (MIC). However, for Enterobacter and indole-pos. Proteus species, the MBC of BL-S786 and cefamandole was usually .ltoreq.8-fold higher than the MICs. Cefoxitin, on the other hand, showed little MIC/MBC variations against indole-pos. Proteus species. Inoculum size had only a small effect on the MICs against most gram-neg. species.
Effect of clavulanic acid on anaerobic bacteria resistant to beta-lactam antibiotics
Effect of clavulanic acid on anaerobic bacteria resistant to beta-lactam antibiotics. Wuest, Juerg; Wilkins, Tracy D. (Inst. Med. Microbiol., Univ. Zurich, Zurich, Switz.). Antimicrob. Agents Chemother., 13(1), 130-3 (English) 1978. CODEN: AMACCQ. ISSN: 0066-4804. DOCUMENT TYPE: Journal CA Section: 3 (Biochemical Interactions) The min. inhibitory concns. of penicillin G [61-33-6] and cephalothin [153-61-7] necessary to inhibit growth of most anaerobic bacteria were decreased to a susceptible level by 1-5 mg of clavulanic acid (I) [58001-44-8]/mL. In most cases, min. inhibitory concns. of cefoxitin [35607-66-0] were not affected.
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