Detail of "434-03-7"

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CAS Number:
434-03-7
Name:
Ethisterone
Molecular Structure:
Formula:
C₂₁H₂₈O₂
Molecular Weight:
312.49
Synonyms:
Gestoral;Testosterone, 17-ethynyl-;17-Hydroxy-17-alpha-pregn-4-en-20-yn-3-one;Trosinone;Ora-Lutin;Etisterona [INN-Spanish];Progestin P;Lutocylol;17-alpha-Pregn-4-en-20-yn-3-one, 17-hydroxy-;Ethinyltestosterone;Ethinyl testosterone;(10R,13S,17S)-17-ethynyl-17-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one;Prone;Prodoxan;Anhydroxyprogesterone;Colutoid;17-ethynyl-17-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one;17-alpha-Ethynyltestosterone;17alpha-Ethynyltestosterone;Etisterone [DCIT];Aethisteronum;17-Ethynyl-17beta-hydroxyandrost-4-en-3-one;Androst-4-en-3-one, 17alpha-ethynyl-17-hydroxy-;Produxan;17-Ethinyltestosterone;Aethisteron;(17S)-17-ethynyl-17-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one;17.alpha.-Pregn-4-en-20-yn-3-one, 17-hydroxy-;Progestoral;Progestolets;Ethisteronum [INN-Latin];Progestab;Pregn-4-en-20-yn-3-one,17-hydroxy-,(17R)-;Primolut C;Ethynyltestosterone;17.alpha.-Ethynyltestosterone;Prodroxan;Pregn-4-en-20-yn-3-one, 17-hydroxy-, (17.alpha.)-;Ethisterone [BAN:INN];Androst-4-en-3-one, 17.alpha.-ethynyl-17-hydroxy-;Pregn-4-en-20-yn-3-one, 17-hydroxy-, (17alpha)- (9CI);17-Ethinyl testosterone;17-beta-Hydroxy-17-alpha-ethynyl-4-androsten-3-one;Nugestoral;Pranone;Prolutol;
EINECS:
207-096-5
Density:
1.13 g/cm³
Melting Point:
263-269 °C(lit.)
Boiling Point:
446.4 °C at 760mmHg
Flash Point:
190.2 °C
Appearance:
Off-white powder
Hazard Symbols:
Xn
Risk Codes:
40-48
Safety:
22-24/25 Details
Transport Information:
UN 2811

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Reference

Standard chemical samples: Standard chemical samples. Communication II. Use of thin-layer chromatography for the qualitative characterization of standard samples of the State Pharmacopeia of the USSR, tenth edition (cortisone acetate, prednisone, testosterone propionate, and pregnin). Arzamastsev, A. P.; Yaskina, D. Z.; Gritsenko, S. V.; Shadrina, L. S.There are some reagents with their cas registry numbers 57-85-2 and 61376-87-2 are used in this study.; Pakholkov, G. V. (USSR). Sb. Nauchn. Tr. - Tsentr. Aptechn. Nauchno-Issled. Inst., 13, 205-13 (Russian) 1975. CODEN: STTAAK. DOCUMENT TYPE: Journal CA Section: 64 (Pharmaceutical Analysis) Thin-layer chromatog. on silica gel was used to qual. identify cortisone acetate [50-04-4], prednisone [53-03-2], testosterone propionate [57-85-2], and pregnin [434-03-7]. Solvent systems are described and Rf values are included for each of these compds. plus epicortisol 21-monoacetate [61376-87-2] and 20-hydroxyprednisone [600-92-0]. The latter 2 compds. cannot be distinguished by uv spectra from cortisone acetate and prednisone, resp. .

The in vitro uptake of some oral contraceptive steroids by magnesium trisilicate: The in vitro uptake of some oral contraceptive steroids by magnesium trisilicate. Khalil, Saleh A. H.; Iwuagwu, M. (Sch. Pharm., Univ. Benin, Benin City, Nigeria). J. Pharm. Pharmacol., 28, Suppl. 47P (English) 1976. CODEN: JPPMAB. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) The extent of monolayer adsorption of 4 steroids by magnesium trisilicate [1343-90-4] (1% aq. suspension) at 37.degree.C was in the order ethisterone [434-03-7] > mestranol [72-33-3] > norethisterone [68-22-4] > ethinylestradiol [57-63-6]. The extent of adsorption was inversely related to the polarity (aq. soly.) of the steroids. Incomplete desorption was obsd. in elution expts. with the adsorbed steroids in both water and 0.05N HCl. In dissoln. tests with Anovlar 21 tablets, magnesium trisilicate (0.5%) produce almost complete redn. in the amt. of norethisterone remaining in soln.Except for chemicals metioned above, 72-33-3 and 57-63-6 are also used. after 3 h. .

Detail of "434-03-7"

Ethisterone

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CAS No.434-03-7 Ethisterone

CAS No.434-03-7 Ethisterone

CAS No.434-03-7 Ethisterone

CAS No.434-03-7 Ethisterone

CAS No.434-03-7 Ethisterone

CAS No.434-03-7 Ethisterone

CAS No.434-03-7 Ethisterone

CAS No.434-03-7 Ethisterone

CAS No.434-03-7 Ethisterone

CAS No.434-03-7 Ethisterone

CAS No.434-03-7 Ethisterone

CAS No.434-03-7 Ethisterone

CAS No.434-03-7 Ethisterone

CAS No.434-03-7 Ethisterone

CAS No.434-03-7 Ethisterone

CAS No.434-03-7 Ethisterone

CAS No.434-03-7 Ethisterone

CAS No.434-03-7 Ethisterone

CAS No.434-03-7 Ethisterone

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CAS No.434-03-7 Ethisterone

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CAS No.434-03-7 Ethisterone

CAS No.434-03-7 Ethisterone

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CAS No.434-03-7 Ethisterone

CAS No.434-03-7 Ethisterone

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CAS No.434-03-7 Ethisterone

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