Detail of > 50-63-5
- CAS Number:
- 50-63-5
- Name:
Chloroquine diphosphate
- Formula:
- C18H26ClN3.2(H3PO4)
- Molecular Structure:
- Synonyms:
- Nivaquine B;Chloroquin diphosphate;Sanoquin;Arolen;Tanakene;Aralen;Chingamin phosphate;Gontochin phosphate;Khingamin;Chingamin;1,4-Pentanediamine,N4-(7-chloro-4- quinolinyl)-N1,N1-diethyl-,phosphate (1:2);Aralen phosphate;Arechin;Aralen (TN);Chloroquine phosphate;Resochin;Aralen diphosphate;7-Chloro-4-[(4-diethylamino-1-methylbutyl)amino]quinoline diphosphate;Resoquine;Resochin diphosphate;Quinoline, 7-chloro-4-[[4- (diethylamino)-1-methylbutyl]amino]-, phosphate (1:2);Quinoline, 7-chloro-4-[[4-(diethylamino)-1-methylbutyl]amino]-, phosphate;Delagil;Prestwick_867;Quinoline, 7-chloro-4-(4-diethylamino-1-methyl-butylamino)-, diphosphate;Quingamine;
- Molecular Weight:
- 515.92
- EINECS:
- 200-055-2
- Melting Point:
- 200 °C (dec.)(lit.)
- Boiling Point:
- 460.6 °C at 760 mmHg
- Flash Point:
- 232.3 °C
- Solubility:
- H2O: 50 mg/mL, clear
- Appearance:
- White Solid
- Hazard Symbols:
Xn- Risk Codes:
- 22-40-20/21/22
- Safety:
- 22-24/25-36Details
- Transport Information:
- UN 1544
- Deleted CAS:
- 69698-56-2|6384-82-3
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Reference
- Effect of antirheumatic agents on the metabolism of collagen proteins
- Effect of antirheumatic agents on the metabolism of collagen proteins. Klebanov, B. M.; Tishchenko, R. I. (Kiev. NII Farmakol. Toksikol, Kiev, USSR). Farmakol. Toksikol. (Kiev), 17, 52-5 (Russian) 1982. CODEN: FATOBP. ISSN: 0430-0939. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) In rats with cotton-ball implants, the formation of granulation-fibrous tissue was decreased by daily injections of mephenamin [341-69-5] and chingamin [50-63-5] and, in lesser degree, by butadione [50-33-9] and indomethacin [53-86-1]. None of these drugs affected the maturation of collagen, although chingamin and salicylate [69-72-7] accelerate collagen catabolism, and mephenamin and chingamin depress synthesis.
- Spectrophotometric determination of chloroquine phosphate in pharmaceutical formulations
- Spectrophotometric determination of chloroquine phosphate in pharmaceutical formulations. Narayanan, M. N.; Raghupratap, D. (Dep. Pharm. Sci., Andhra Univ., Waltair, India). Indian Drugs, 21(8), 338-42 (English) 1984. CODEN: INDRBA. ISSN: 0019-462X. DOCUMENT TYPE: Journal CA Section: 64 (Pharmaceutical Analysis) Chloroquine phosphate (I phosphate) [50-63-5] is detd. in aq. solns. or dilns. of tablets or injections by mixing with NH4 molybdate, reducing with SnCl2, extg., Molybdenum Blue with iso-BuOH, and measuring the absorbance at 720 nm. Recoveries were 99.62-100.1%, and compared well with std. methods.
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