Reference

Process for preparation of 2-amino-3,5-dibromobenzaldehyde in high purity and yield

Process for preparation of 2-amino-3,5-dibromobenzaldehyde in high purity and yield. Song, Hyun Sam (S. Korea ). Repub. Korean Kongkae Taeho Kongbo KR 2002049673 A 26 Jun 2002,No pp. given (Korean). (Korea, Republic Of). CODEN: KRXXA7. CLASS: ICM: C07C223-06. APPLICATION: KR 2000-78888 20 Dec 2000. DOCUMENT TYPE: Patent CA Section: 25 (Benzene, Its Derivatives, and Condensed Benzenoid Compounds) Provided is a process for producing 2-amino-3,5-dibromobenzaldehyde in high purity and yield from 2-amino-3,5-dibromobenzoic hydrazide, which can reduce byproducts and improve quality. The 2-amino-3,5-dibromobenzaldehyde(formula 1) is produced by mixing and reacting the 2-amino-3,5-dibromobenzoic hydrazide(formula 2) as a starting material, 0.1-2 wt.(based on the starting material) of a ketone compd., 0.05-0.5 wt.pts. of an oxidizing agent, and 0.5-2.0 wt.pts. of water in 2-11 wt.pts. of a mixed solvent at a temp. of 0-80° for 1-10 h, followed by filtering, washing, and recovering the solvent. The mixed solvent comprises a polar solvent, org. and inorg. 97096-13-4 and 50910-55-9 which are cas registry numbers of chemicals are mentioned. alkalis, an antioxidant, and water in the wt. ratio of 1.0-4.0:0.5-1.5:0.001-0..0-5.0. .