Detail of "536-90-3"

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CAS Number:
536-90-3
Name:
m-Anisidine
Molecular Structure:
Formula:
C₇H₉NO
Molecular Weight:
123.17
Synonyms:
1-Amino-3-methoxybenzene;3-Aminoanisole;3-Methoxyaniline;3-Methoxybenzenamine;3-Methoxyphenylamine;NSC 7631;m-Aminoanisole;m-Aminomethoxybenzene;m-Anisylamine;m-Methoxyaniline;Benzenamine, 3-methoxy-;
EINECS:
208-651-4
Density:
1.064 g/cm³
Melting Point:
?1-1 °C(lit.)
Boiling Point:
251 °C at 760 mmHg
Flash Point:
109.6 °C
Solubility:
<0.1 g/100 mL at 19 °C in water
Appearance:
Pale yellow oily liquid or dark red liquid
Hazard Symbols:
T+, N, Xn
Risk Codes:
22-36/37/38-50/53-51/53-33-26/27/28
Safety:
26-60-61-45-36/37-28B Details
Transport Information:
UN 2431 6.1/PG 3

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Reference

Preparation of heteroaryl hydrazides with G protein-coupled receptor (GPCR) desensitization inhibitory activity: All Rights Reserved. Preparation of heteroaryl hydrazides with G protein-coupled receptor (GPCR) desensitization inhibitory activity. Delong, Mitchell A.; Sznaidman, Marcos L.; Oakley, Robert H.; Eckhardt, Allen E.; Hudson, Christine; Yingling, Jeffrey D.; Peel, Michael; Richardson, Thomas E.; Murray, Claire Louise; Rao, Byappanahally N. Narasinga; Heasley, Brian H.; Patel, Paresma R. ( Aerie Pharmaceuticals, Inc., USA). PCT Int. Appl. WO 2007008942 A2 18 Jan 2007, 93pp. DESIGNATED STATES: W: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC; RW: AT, BE, BF, BJ, CF, CG, CH, CI, CM, CY, DE, DK, ES, FI, FR, GA, GB, GR, IE, IS, IT, LU, MC, ML, MR, NE, NL, PT, SE, SN, TD, TG, TR. (English). (World Intellectual Property Organization). CODEN: PIXXD2. 919523-74-3 and 536-90-3 are also in the experiment. CLASS: ICM: A61K. APPLICATION: WO 2006-US26976 11 Jul 2006. PRIORITY: US 2005-698190P 11 Jul 2005. DOCUMENT TYPE: Patent CA Section: 27 (Heterocyclic Compounds (One Hetero Atom)) Section cross-reference(s): 1, 28, 63 Title compds. [I; R1-R5 = H, halo, alkyl, amino, NO2, cyano, heteroaryl, CO2H, carbonylamino, aminosulfonyl, acyl, etc.; R6 = H, alkyl; R7 = H, alkyl, alkoxy; A = specified 5-6 membered heteroaryl; X = NR6], were prepd. to influence, inhibit or reduce the action of a G-protein receptor kinase. Thus, title compd. (II) (prepn. outlined) inhibited G protein-coupled receptor kinases GRK-2 and GRK-3 with Ki = 10-100 nM. .

Synthesis and antiviral and antitumor activities of 2H-[1,2,3]triazolo[4,5-d]pyrimidines and 1H-, 2H-, and 3H-[1,2,3]triazolo[4,5-d]pyrimidin-5(4H)-one-7(6H)-thiones: All Rights Reserved. Synthesis and antiviral and antitumor activities of 2H-[1,2,3]triazolo[4,5-d]pyrimidines and 1H-, 2H-, and 3H-[1,2,3]triazolo[4,5-d]pyrimidin-5(4H)-one-7(6H)-thiones. Islam, Rafiqul; Nagamatsu, Tomohisa (Department of Drug Discovery and Development, Division of Pharmaceutical Sciences, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Tsushima, Okayama 700-8530, Japan). Heterocycles, 68(11), 2387-2402 (English) 2006 Japan Institute of Heterocyclic Chemistry. CODEN: HTCYAM. ISSN: 0385-5414. DOCUMENT TYPE: Journal CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Section cross-reference(s): 1, 10 This paper describes a facile synthesis of 2-aryl-2H-[1,2,3]triazolo[4,5-d]pyrimidine-5,7(4H,6H)-diones, e.g., I, and 7-amino-2-aryl-5-phenyl-2H-[1,2,3]triazolo[4,5-d]pyrimidines, e.g., II, prepd. by oxidative heterocyclization of 6-amino-5-arylazopyrimidine-2,4(1H,3H)-diones, e.g.There are some commonly used reagents with their cas registry numbers 95-64-7 and 536-90-3 in this article., III, and 4,6-diamino-5-arylazo-2-phenylpyrimidines, e.g., IV, resp. as well as evaluation of their antiviral and antitumor activities in vitro. .

Detail of "536-90-3"

m-Anisidine

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Reference