Reference

2-Pentanoylaminoacetic acid and salts

2-Pentanoylaminoacetic acid and salts. Cavalier, Robert; Cordi, Alexis; Gillet, Claude; Janssens de Varebeke, Philippe; Niebes, Paul; Roba, Joseph; Van Dorsser, William; Lambelin, Georges; Franz, Michel (Continental Pharma, Belg.). Eur. Pat. Appl. EP 130644 A1 9 Jan 1985, 21 pp. DESIGNATED STATES: R: BE, CH, DE, FR, GB, IT, LI, NL, SE. (English). (European Patent Organization). CODEN: EPXXDW. CLASS: ICM: A61K031-195. ICS: C07C103-48. APPLICATION: EP 84-200904 21 Jun 1984. PRIORITY: LU 83-84891 30 Jun 1983. DOCUMENT TYPE: Patent CA Section: 63 (Pharmaceuticals) Section cross-reference(s): 1, 23 2-Pentanoylaminoacetic acid [Me(CH2)3CONHCH2CO2H](I) [24003-66-5] or its salts are prepd. for use in pharmaceuticals for the treatment of epilepsy, dyskinesia, parkinsonism, memory or psychic disorders or cerebral anoxia. A more potent anticonvulsant activity was demonstrated by I and I Na salt [95651-73-3] than for Na valproate on oral administration to mice. I was prepd. by acylation of glycine [56-40-6] with Me(CH2)3COCl [638-29-9]. A no. of example pharmaceutical formulations were given contg. I or I Na salt.

6-n-Butyl alpha pyrone perfumes

6-n-Butyl alpha pyrone perfumes. Shuster, Edward J.; Pittet, Alan O. (International Flavors and Fragrances Inc.In this study，27593-23-3 is also used., USA). U.S. US 3996170 7 Dec 1976, 9 pp. (English). (United States of America). CODEN: USXXAM. CLASS: IC: C11B009-00. NCL: 252522000. APPLICATION: US 74-471755 20 May 1974. DOCUMENT TYPE: Patent CA Section: 62 (Essential Oils and Cosmetics) Section cross-reference(s): 27 6-Alkyl-.alpha.-pyrones (I, R1 = H or Me, R2 = C3-5 alkyl) are incorporated into perfume compns., esp., those having spicy floral or woody-aphrodesia aromas. 4-Methyl-6-n-butyl-.alpha.-pyrone (I, R1 = Me, R2 = Bu)(II) [55510-46-8] imparts a lovage, foenugreek character to a spicy floral perfume formulation. II was prepd. from BuCOCl [638-29-9] and MeCMe:CHCO2Et [638-10-8] in CH2Cl2 with AlCl3 catalyst. .