Detail of "6938-94-9"

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CAS Number:
6938-94-9
Name:
Hexanedioic acid,1,6-bis(1-methylethyl) ester
Superlist Name:
Diisopropyl adipate
Molecular Structure:
Formula:
C₁₂H₂₂O₄
Molecular Weight:
230.30
Deleted CAS:
121879-14-9
Synonyms:
Adipicacid, diisopropyl ester (6CI,7CI,8CI);Hexanedioic acid, bis(1-methylethyl)ester (9CI);Ceraphyl 230;Crodamol DA;Iso Adipat;Isopropyl adipate;NSC 56587;Nikkol DID;Schercemol DIA;Standamul DIPA;BRN 1785346;
EINECS:
230-072-0
Density:
0.982 g/cm³
Boiling Point:
252.6 °C at 760 mmHg
Flash Point:
109.8 °C
Risk Codes:
36/37/38
Safety:
26-36/37/39 Details

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Topical antiinflammatory and analgesic gel containing clidanac: Topical antiinflammatory and analgesic gel containing clidanac. Kigasawa, Kazuo; Ohtani, Hideaki; Kanezuka, Toshiyuki (Takeda Chemical Industries, Ltd. , Japan). Eur. Pat. Appl. EP 104037 A1 28 Mar 1984, 33 pp. DESIGNATED STATES: R: BE, CH, DE, FR, GB, IT, LI, NL, SE. (English). (European Patent Organization). CODEN: EPXXDW. CLASS: IC: A61K009-06; A61K031-19. APPLICATION: EP 83-305297 9 Sep 1983. PRIORITY: JP 82-158938 14 Sep 1982. DOCUMENT TYPE: Patent CA Section: 63 (Pharmaceuticals) A topical gel contains clidanac (I) [34148-01-1] or its salt 0.03-1.5, gelling agent 0.5-5.0, neutralizer 0.3-4.0, solubilizer 30-60, and H2O 35-65% by wt. An absorption promoter, 0.3-10%, can be added also. Thus, 0.1 g HiVisWako 104 [89286-85-1] and 0.7 g hydroxyethyl cellulose [9004-62-0] were swollen in 30 g H2O. I, 0.There are some reagents like 90825-41-5 is used in this study.1 g, was dissolved in 1,3-butylene glycol [107-88-0] 12, diiso-Pr adipate [6938-94-9] 2.0, and EtOH 30 g, and this soln. was added to the gelling agent mixt. Diisopropanolamine [110-97-4] 0.7 g, was dissolved in 10 g H2O and added to the mixt., and H2O was added to 100 g. The gel had good storage stability (98.8% of original activity after 60 days at 40° and 75 or 90% relative humidity). The antiinflammatory and analgesic potency were demonstrated in 9 animal systems. .

Etofenamate topical cream: Etofenamate topical cream. Dell, Hans Dieter; Kraus, Reinhold; Schierstedt, Detlef (Troponwerke G.m.b.H. und Co. K.-G., Fed. Rep. Ger.). Ger. Offen. DE 3323833 A1 3 Jan 1985, 11 pp. (German). (Germany). CODEN: GWXXBX. CLASS: ICM: A61K031-245. APPLICATION: DE 83-3323833 1 Jul 1983. DOCUMENT TYPE: Patent CA Section: 63 (Pharmaceuticals) A topical cream formulation of 5-40% etofenamate (I) [30544-47-9] contains medium-chain triglycerides, esters of C2-18 alcs. with C6-18 carboxylic acids, and long-chain alcs., and is prepd. by mixing the ingredients and homogenizing at 40-60°. The creams were bioequiv. to the com. alc. gel in clin. tests. A cream contained: I 50, diiso-Pr adipate [6938-94-9] 820, Cremophor EL emulsifier 50, and Aerosil 80 mg.