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10532-14-6

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10532-14-6 Usage

Description

[1,1'-Biphenyl]-4-acetic acid, α-methyl-, (S)-, also known as esomeprazole, is a chemical compound with the molecular formula C16H14O2. It is a proton pump inhibitor that functions to reduce stomach acid production, making it a valuable pharmaceutical agent for treating various gastrointestinal conditions.

Uses

Used in Pharmaceutical Industry:
Esomeprazole is used as a medication for treating conditions caused by excess stomach acid, such as gastroesophageal reflux disease (GERD), peptic ulcers, and other related ailments. It operates by blocking the enzyme in the stomach wall responsible for acid production, thereby decreasing acid levels and providing relief from symptoms.
Used in Gastroenterology:
In the field of gastroenterology, esomeprazole is utilized as a proton pump inhibitor to manage acid-related disorders. Its effectiveness in reducing stomach acid makes it a preferred choice for patients suffering from GERD and peptic ulcers, improving their quality of life and aiding in the healing process of the affected areas.
Used in Drug Delivery Systems:
Esomeprazole is typically taken orally in the form of delayed-release capsules or tablets, which are designed to release the medication slowly over time. This controlled-release formulation helps maintain an effective concentration of the drug in the body, ensuring continuous relief from symptoms and allowing for once-daily dosing.

Check Digit Verification of cas no

The CAS Registry Mumber 10532-14-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,5,3 and 2 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 10532-14:
(7*1)+(6*0)+(5*5)+(4*3)+(3*2)+(2*1)+(1*4)=56
56 % 10 = 6
So 10532-14-6 is a valid CAS Registry Number.

10532-14-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name (2S)-2-(4-phenylphenyl)propanoic acid

1.2 Other means of identification

Product number -
Other names UNII-E4ZV1V9C3W

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:10532-14-6 SDS

10532-14-6Relevant articles and documents

Palladium-catalyzed hydrodefluorination of fluoroarenes

Brodney, Michael A.,Gair, Joseph J.,Giroux, Simon,Grey, Ronald L.

, p. 131 - 146 (2021/06/18)

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Palladium catalyzed hydrodefluorination of fluoro-(hetero)arenes

Gair, Joseph J.,Grey, Ronald L.,Giroux, Simon,Brodney, Michael A.

supporting information, p. 2482 - 2487 (2019/04/10)

Palladium catalyzed hydrodefluorination was developed for fine-tuning the properties of fluoro-(hetero)aromatic compounds. The robust reaction can be set up in air, requires only commercially available components, and tolerates a variety of heterocycles and functionalities relevant to drug discovery. Given the prevalence of fluorine incorporation around metabolic hotspots, the corresponding deuterodefluorination reaction may prove useful for converting fluorinated libraries to deuterated analogues to suppress the oxidative metabolism by kinetic isotope effects.

Visible-Light-Driven External-Reductant-Free Cross-Electrophile Couplings of Tetraalkyl Ammonium Salts

Liao, Li-Li,Cao, Guang-Mei,Ye, Jian-Heng,Sun, Guo-Quan,Zhou, Wen-Jun,Gui, Yong-Yuan,Yan, Si-Shun,Shen, Guo,Yu, Da-Gang

, p. 17338 - 17342 (2019/01/04)

Cross-electrophile couplings between two electrophiles are powerful and economic methods to generate C-C bonds in the presence of stoichiometric external reductants. Herein, we report a novel strategy to realize the first external-reductant-free cross-electrophile coupling via visible-light photoredox catalysis. A variety of tetraalkyl ammonium salts, bearing primary, secondary, and tertiary C-N bonds, undergo selective couplings with aldehydes/ketone and CO2. Notably, the in situ generated byproduct, trimethylamine, is efficiently utilized as the electron donor. Moreover, this protocol exhibits mild reaction conditions, low catalyst loading, broad substrate scope, good functional group tolerance, and facile scalability. Mechanistic studies indicate that benzyl radicals and anions might be generated as the key intermediates via photocatalysis, providing a new direction for cross-electrophile couplings.

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