1461-22-9Relevant articles and documents
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Friedrich,Vartanian
, p. 159,160-165 (1976)
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Highly stereoselective addition to alkoxy or hydroxy ketones using an α-stannyl ester-stannous chloride system in a chelation-controlled manner
Yasuda,Okamoto,Sako,Baba
, p. 157 - 158 (2001)
The reaction of an α-stannyl ester with α-alkoxy or hydroxy ketones in the presence of SnCl2 gave aldol-type products with high selectivity in a chelation-controlled manner.
Sisido et al.
, p. 439,443 (1967)
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Kuivila
, p. 284 (1960)
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Beak,Moje
, p. 1320 (1974)
Cyclopropenone.
Breslow,Ryan
, p. 3073 - 3073 (1967)
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Armitage,Tarassoli
, p. 1225 (1973)
Preparation and characterization of dimethoxyphosphine
Centofanti
, p. 1131 - 1133 (1973)
Dimelhoxyphosphine, (CH3O)2PH, has been obtained from the reaction of PF2H, CH3OH, and pyridine and from the carefully controlled reduction of (CH3O)2PCl by (C4H9)3SnH
Cohen,Dillard
, p. 421,423,426 (1970)
A simple method for preparing some cyclopropylcarbinyl compounds
Peterson, Donald J.,Robbins, M.Dwight
, p. 2135 - 2138 (1972)
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Chambers, V. M. A.,Jackson, W. R.,Young, G. W.
, (1971)
Kuivila, H. G.,Menapace, L. W.
, p. 2165 - 2167 (1963)
Stack, W. F.,Nash, G. A.,Skinner, H. A.
, p. 2122 - 2125 (1965)
Seyferth, D.,Yamazaki, H.,Alleston, D. L.
, p. 703 - 706 (1963)
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Carlsson,Ingold
, p. 1055 (1968)
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Poutsma, M. L.,Ibaria, P. A.
, p. 2848 - 2855 (1969)
Abraham, M. H.
, (1971)
Organic tin compound cycle application Stille method of synthesis of biphenyl
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Paragraph 0051; 0055, (2017/05/12)
The invention provides a method for synthesizing diphenyl through Stille reaction recycling with an organotin compound, and relates to a method for preparing diphenyl through a Stille reaction. A purpose of the present invention is to solve the problem of low organotin utilization rate of the existing Stille method for preparing the diphenyl compound. The method comprises: 1, adopting tri-butyltin chloride and bromobenzene as raw materials, and carrying out a reaction under the effect of a Grignard reagent to synthesize tributylphenyltin; 2, carrying out a reaction of a mixed solution of halogenated benzene, tributylphenyltin, cuprous iodide, lithium chloride, palladium(triphenylphosphine)dichloride and cesium fluoride DMF to prepare diphenyl, and collecting the filter residue; 3, dissolving the filter residue with acetone, dissolving the insoluble matter with absolute alcohol, and concentrating to obtain fluorotributyltin; and 4, converting the tin fluoride into the organic tin chloride with saturated ammonium chloride tetrahydrofuran. According to the present invention, the synthesis process conditions are optimized, the highest yield of the diphenyl compound achieves 97%, and the effective separation utilization of the organic tin chloride is achieved.
Indium-mediated regioselective synthesis of ketones from arylstannanes under solvent-free ultrasound irradiation
Lo Fiego, Marcos J.,Badajoz, Mercedes A.,Domini, Claudia,Chopa, Alicia B.,Lockhart, María T.
, p. 826 - 832 (2013/03/14)
The solvent-free indium-promoted reaction of alkanoyl chlorides with sterically and electronically diverse arylstannanes is a simple and direct method for the regioselective synthesis of primary, secondary and tertiary alkyl aryl ketones in good to excellent isolated yields (42-84%) under mild and neutral conditions. The protocol is also adequate for the synthesis of aryl vinyl ketones. Reaction times are drastically reduced (from 3-32 h to 10-70 min) under ultrasonic irradiation. Evidences for the involvement of a homolytic aromatic ipso-substitution mechanism, in which indium metal acts as radical initiator, are presented. It is possible the transference of two aryl groups from tin, thus improving effective mass yield, working with diarylstannanes as starting substrates.