100429-08-1

Basic information

• Product Name: 8-hydroxy-5-[(1R)-1-hydroxy-2-{[(2R)-1-(4-methoxyphenyl)propan-2-yl]amino}ethyl]quinolin-2(1H)-one hydrochloride (1:1)
• Synonyms: 2(1H)-Quinolinone, 8-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl ]amino]ethyl]-, monohydrochloride; Carmoterol Hydrochloride
• CAS NO: 100429-08-1
• Molecular Formula: C₂₁H₂₅ClN₂O₄
• Molecular Weight: 404.8872
• Mol File: 100429-08-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 649.1°C at 760 mmHg
• Flash Point: 346.4°C
• Vapor Pressure: 9.75E-18mmHg at 25°C
• CAS DataBase Reference: 8-hydroxy-5-[(1R)-1-hydroxy-2-{[(2R)-1-(4-methoxyphenyl)propan-2-yl]amino}ethyl]quinolin-2(1H)-one hydrochloride (1:1)(CAS DataBase Reference)
• NIST Chemistry Reference: 8-hydroxy-5-[(1R)-1-hydroxy-2-{[(2R)-1-(4-methoxyphenyl)propan-2-yl]amino}ethyl]quinolin-2(1H)-one hydrochloride (1:1)(100429-08-1)
• EPA Substance Registry System: 8-hydroxy-5-[(1R)-1-hydroxy-2-{[(2R)-1-(4-methoxyphenyl)propan-2-yl]amino}ethyl]quinolin-2(1H)-one hydrochloride (1:1)(100429-08-1)

Safety Data

• Hazardous Substances Data: 100429-08-1(Hazardous Substances Data)

Upstream product

• 100429-06-9 8-benzyloxy-5-{(1S)-1-hydroxy-2-[N-((1S)-2-(p-methoxyphenyl)-1-methylethyl)amino]ethyl}carbostyril 
• 1052689-06-1 8-benzyloxy-5-{(1R)-1-hydroxy-2-[N-((lR)-2-(p-methoxy phenyl)-1-methylethyl) amino] ethyl} carbostyril hydrochloride 
• 108-20-3 di-isopropyl ether 
• 57434-96-5 5-acetyl-8-hydroxyquinoline hydrochloride 
• 100331-93-9 5-Acetyl-8-benzyloxyquinoline-N-oxide 
• 26872-48-0 1-(8-benzyloxyquinolin-5-yl)ethanone 
• 2598-31-4 5-acetyl-8-hydroxyquinoline 
• 100331-89-3 8-benzyloxy-5-(2-bromoacetyl)-1H-quinolin-2-one 
• 148-24-3 8-quinolinol 

Relevant articles and documents

Process for the preparation of 8-hydroxy-5-[(1R)-1-hydroxy-2[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]-2(1H)-quinolinone monohydrochloride

The invention relates to a process for the preparation of 8-hydroxy-5-[(1R)-1-hydroxy-2 [[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]-2(1H)-quinolinone monohydrochloride of formula (I). Useful intermediates in the process are also disclosed.

8-HYDROXY-5-[(-HYDROXY-2-[[ (1R)-2-(4-METHOXYPHENYL)-1-METHYLETHYL] AMINO ][ETHYL] -2(1H)-QUINOLINONE MONOHYDROCHLORIDE IN CRYSTALLINE FORM AND THE PROCESS FOR ITS PREPARATION

The invention relates to 8-hydroxy-5- [(1 R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methyl ethyl] amino] ethyl] -2 (1 H)-quinolinone monohydrochloride of formula (I) in crystalline form, provided with suitable characteristics in order to be used for the