1020701-51-2

Basic information

• Product Name: N-(2-{5-methoxy-1-[(4-methylphenyl)sulfonyl]-1H-indol-3-yl}ethyl)acetamide
• Synonyms: N-(2-{5-methoxy-1-[(4-methylphenyl)sulfonyl]-1H-indol-3-yl}ethyl)acetamide
• CAS NO: 1020701-51-2
• Molecular Weight: 386.472
• Mol File: 1020701-51-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-(2-{5-methoxy-1-[(4-methylphenyl)sulfonyl]-1H-indol-3-yl}ethyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-{5-methoxy-1-[(4-methylphenyl)sulfonyl]-1H-indol-3-yl}ethyl)acetamide(1020701-51-2)
• EPA Substance Registry System: N-(2-{5-methoxy-1-[(4-methylphenyl)sulfonyl]-1H-indol-3-yl}ethyl)acetamide(1020701-51-2)

Safety Data

• Hazardous Substances Data: 1020701-51-2(Hazardous Substances Data)

Upstream product

• 608-07-1 2-(5-methoxyindol-3-yl)ethylamine 
• 61675-19-2 5-methoxy-3-(2-nitroethylenyl)-1H-indole 
• 10601-19-1 5-methoxyindole-3-carboxaldehyde 
• 1006-94-6 5-methoxylindole 
• 73-31-4 5-methoxy-N-acetyl-tryptamine 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 1020701-52-3 N-(2-(5-hydroxy-1-tosyl-1H-indol-3-yl)ethyl)acetamide 
• 73-31-4 5-methoxy-N-acetyl-tryptamine 

Relevant articles and documents

A facile and versatile electro-reductive system for hydrodefunctionalization under ambient conditions

A general electrochemical system for reductive hydrodefunctionalization is described, employing the inexpensive and easily available triethylamine (Et3N) as a sacrificial reductant. This protocol is characterized by facile operation, sustainable conditions, and exceptionally wide substrate scope covering the cleavage of C-halogen, N-S, N-C, O-S, O-C, C-C and C-N bonds. Notably, the selectivity and capability of reduction can be conveniently switched by simple incorporation or removal of an alcohol as a co-solvent.

An environmentally friendly protocol for oxidative halocyclization of tryptamine and tryptophol derivatives

An environmentally friendly and efficient protocol (KX/oxone) for oxidative halocyclization of tryptamine/tryptophol derivatives was developed and demonstrated with 28 examples and concise total synthesis of cyclotryptamine alkaloid protubonines A and B. The distinct advantage of this protocol over all previous methods is that no organic byproduct is generated from a halogenating agent or oxidant, thus greatly reducing the environmental impact of halocyclization and facilitating the post-reaction purification.