1020701-52-3

Basic information

• Product Name: N-(2-(5-hydroxy-1-tosyl-1H-indol-3-yl)ethyl)acetamide
• Synonyms: N-(2-(5-hydroxy-1-tosyl-1H-indol-3-yl)ethyl)acetamide
• CAS NO: 1020701-52-3
• Molecular Weight: 372.445
• Mol File: 1020701-52-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(2-(5-hydroxy-1-tosyl-1H-indol-3-yl)ethyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-(5-hydroxy-1-tosyl-1H-indol-3-yl)ethyl)acetamide(1020701-52-3)
• EPA Substance Registry System: N-(2-(5-hydroxy-1-tosyl-1H-indol-3-yl)ethyl)acetamide(1020701-52-3)

Safety Data

• Hazardous Substances Data: 1020701-52-3(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 73-31-4 5-methoxy-N-acetyl-tryptamine 
• 1020701-51-2 N-(2-{5-methoxy-1-[(4-methylphenyl)sulfonyl]-1H-indol-3-yl}ethyl)acetamide 

Downstream Products

• 1020701-53-4 N-(2-{1-[(4-Methylphenyl)sulfonyl]-5-[2-(1-piperidinyl)ethoxy]-1H-indol-3-yl}ethyl)acetamide 

Relevant articles and documents

Trideuteromethylation Enabled by a Sulfoxonium Metathesis Reaction

A conceptually novel sulfoxonium metathesis reaction between TMSOI and cost-effective DMSO-d6 is developed for the efficient generation of a new trideuteromethylation reagent TDMSOI. The new reagent TDMSOI is produced highly efficiently by simply heating a mixture of TMSOI and DMSO-d6 and directly used for subsequent trideuteromethylation in a "one-pot" operation. The preparative power of the new versatile reagent and the "one-pot" protocol is demonstrated by its use to install the ?CD3 moiety into broad functionalities including phenols, thiophenols, acidic amines, and enolizable methylene units in high yield and at a useful level of deuteration (>87% D).