103281-33-0 Usage
Description
2,2-Bis(p-Methoxyphenyl)-2-phenylacetophenone is an organic compound that is characterized as a yellow solid. It is a derivative of acetophenone, featuring two p-methoxyphenyl groups and a phenyl group attached to the acetophenone structure.
Uses
Used in Pharmaceutical Industry:
2,2-Bis(p-Methoxyphenyl)-2-phenylacetophenone is used as an intermediate in the preparation of Clomiphene (C587025) impurity. Clomiphene is a medication primarily used to treat infertility in women, and this compound plays a crucial role in the synthesis process to ensure the purity and efficacy of the final product.
As an intermediate, 2,2-Bis(p-Methoxyphenyl)-2-phenylacetophenone contributes to the development of pharmaceuticals by facilitating the synthesis of specific compounds with desired therapeutic properties. Its chemical structure allows for further functionalization and modification, making it a versatile building block in the synthesis of various pharmaceutical agents.
Check Digit Verification of cas no
The CAS Registry Mumber 103281-33-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,2,8 and 1 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 103281-33:
(8*1)+(7*0)+(6*3)+(5*2)+(4*8)+(3*1)+(2*3)+(1*3)=80
80 % 10 = 0
So 103281-33-0 is a valid CAS Registry Number.
103281-33-0Relevant articles and documents
A highly efficient friedel-crafts reaction of tertiary α- hydroxyesters or α-hydroxyketones to α-quaternary esters or ketones
Chen, Long,Zhou, Jian
, p. 2510 - 2515,6 (2012)
A catalytic Friedel-Crafts arylation of α-hydroxyesters or α-hydroxyketones with electron-rich aromatic compounds to furnish α-quaternary esters/ketones has been developed. The cheap and easy to handle catalyst HClO4 (70 %, aq) was identified as a powerful catalyst for this arylation reaction. Copyright
Pinacol-Pinacolone Rearrangement on FeCl3 Modified Montmorillonite K10
Shinde, Ajit B.,Shrigadi, Nilesh B.,Bhat, Ramakrishna P.,Samant, Shriniwas D.
, p. 309 - 314 (2007/10/03)
Pinacol-pinacolone rearrangement was investigated over Fe-modified montmorillonite K10 catalysts in liquid phase. Exceptional activity was found to be associated with FeCl3 impregnated on K10 through its acetonitrile solution. 100% conversion of benzopinacol was observed in 10 minutes. The catalysts are recyclable.
