104819-24-1

Basic information

• Product Name: 1-benzylindole-3-acetic chloride
• Synonyms: 1-benzylindole-3-acetic chloride
• CAS NO: 104819-24-1
• Molecular Weight: 283.757
• Mol File: 104819-24-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-benzylindole-3-acetic chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzylindole-3-acetic chloride(104819-24-1)
• EPA Substance Registry System: 1-benzylindole-3-acetic chloride(104819-24-1)

Safety Data

• Hazardous Substances Data: 104819-24-1(Hazardous Substances Data)

Upstream product

• 4307-97-5 N-benzylindole-3-acetic acid 
• 100-44-7 benzyl chloride 
• 87-51-4 indole-3-acetic acid 

Downstream Products

• 458529-83-4 dimethyl 2-(1-benzyl-1H-indol-3-yl)malonate 
• 56999-27-0 N-methyl-1-benzylindole-3-acetamide 
• 922072-35-3 N-n-butyl-1-benzylindole-3-acetamide 
• 4276-26-0 (N¹-benzyl-3-indolyl)acetamide 
• 56999-28-1 N-ethyl-1-benzylindole-3-acetamide 
• 922036-79-1 N-n-propyl-1-benzylindole-3-acetamide 
• 104819-25-2 ethyl 4-(1-benzylindol-3-yl)-3-oxobutanoate 
• 104819-29-6 methyl 4-(1-benzylindol-3-yl)-oxobutanoate 
• 125923-35-5 methyl (N¹-benzyl-3-indolyl)acetate 
• 104819-27-4 2-[2-(1-Benzyl-1H-indol-3-yl)-acetyl]-malonic acid diethyl ester 
• 104819-28-5 2-(1-Benzyl-1H-indol-3-yl)-1-imidazol-1-yl-ethanone 
• 104819-26-3 2-(1-Benzyl-1H-indol-3-yl)-N,N-diisopropyl-acetamide 

Relevant articles and documents

Palladium-catalyzed intramolecular decarboxylative allylic arylation of α-aryl-γ-methylidene-δ-valerolactones

A palladium-catalyzed intramolecular decarboxylative cyclization of α-aryl-γ-methylidene-δ-valerolactones, followed by olefin isomerization, has been developed to give fused polycyclic aromatic compounds under mild conditions. The process described here can be regarded as a formal decarboxylative allylic arylation without using a pre-formed organometallic nucleophile. The reaction can be conducted on a gram scale and the products thus obtained are further derivatized with ease.

REACTIONS OF β-KETO ESTERS WITH 2-CYANO-1,2,5,6-TETRAHYDROPYRIDINES

Reaction of the sodium salts of β-keto esters 13a and 13b with the 2-cyano-tetrahydropyridines 11 and 12 afforded the 4-substituted piperidine derivatives 21-23.The structures were assigned on the basic of their (1)H-and (13)C-NMR spectra and by comparison with the model compounds 24-26.The stereochemistry and the mechanism of the reactions are discussed.