112780-08-2

Basic information

• Product Name: 3-Hexyn-2-ol, (R)-
• CAS NO: 112780-08-2
• Molecular Formula: C6H10O
• Molecular Weight: 98.1448
• Mol File: 112780-08-2.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: 3-Hexyn-2-ol, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Hexyn-2-ol, (R)-(112780-08-2)
• EPA Substance Registry System: 3-Hexyn-2-ol, (R)-(112780-08-2)

Safety Data

• Hazardous Substances Data: 112780-08-2(Hazardous Substances Data)

Upstream product

• 853685-13-9 trans-2,3,4-Hexatrien 
• 1679-36-3 3-hexyn-2-one 
• 74-96-4 ethyl bromide 
• 2028-63-9 but-3-yn-2-ol 
• 112780-08-2 hex-3-yn-2-ol 
• 1384108-48-8 C₆H₉O₄S^(1-)*Na⁽¹⁺⁾ 
• 65640-71-3 2-benzoyloxy-3-hexyne 
• 928-49-4 hex-3-yne 
• 75-07-0 acetaldehyde 
• 107-00-6 but-1-yne 
• 144587-65-5 4-propenylidene-5-methyl-1,3-dithiolane-2-thione 
• 26494-11-1 3-hexyne-2,5-ditosylate 
• 3031-66-1 3-hexyn-2,5-diol 
• 13254-28-9 but-1-ynylmagnesium bromide 

Downstream Products

• 1679-36-3 3-hexyn-2-one 
• 109-50-2 (R)-(+)-3-Hexyn-2-ol 
• 1384108-66-0 C₆H₉O₄S^(1-)*Na⁽¹⁺⁾ 
• 129364-62-1 (S)-(-)-3-Hexyn-2-ol 
• 1341133-85-4 (E)-3-phenylhex-3-en-2-ol 

Relevant articles and documents

Phosphine-Catalyzed Intermolecular Annulations of Fluorinated ortho-Aminophenones with Alkynones – The Switchable [4+2] or [4+2]/[3+2] Cycloaddition

A phosphine-catalyzed intermolecular annulation reaction of functionalized ortho-aminoacetophenones with alkynones has been disclosed in this paper. A variety of 2-alkynylquinolines and benzo-fused indolizine were selectively afforded in moderate to good yields at different reaction temperatures and with different phosphine catalysts via the in situ generated zwitterionic intermediate derived from alkynone and phosphine. (Figure presented.).

In situ generation of nucleophilic allenes by the gold-catalyzed rearrangement of propargylic esters for the highly diastereoselective formation of intermolecular C(sp3)-C(sp2) bonds

New perspectives, in particular for the synthesis of isochromane derivatives (see scheme), are provided by the title reaction. Excellent diastereoselectivites are achieved in this reaction which proceeds through a gold-catalyzed 1,3-acyloxy migration. In some cases exclusively the Z isomer is detected. Copyright

Synthesis of novel 2H,5H-dihydrofuran-3-yl ketones via ISNC reactions

Unique 1-[2H,5H-dihydrofur-3-yl]ketones have been synthesized from propargylic nitroethers via intramolecular cycloadditions involving silyl nitronates. Various substituent groups were placed on the 2 and 5 positions of the dihydrofuran rings. We examined the scope of the long-range coupling in proton NMR of the oxo-dihydrofuran products. The identities of the diastereomers resulting from the Michael addition/cycloaddition reactions were tentatively assigned for the first time. CAChe MNDO PM5 and CONFLEX programs were engaged to assist with the identification of these stereoisomers. The reaction times and conditions for these oxo-dihydrofurans were found to be different than that of the published dihydrofuranals, which led us to propose a different mechanism.