122918-25-6Relevant articles and documents
Synthesis and antiprotozoal activity of pyridyl analogues of pentamidine
Bakunova, Svetlana M.,Bakunov, Stanislav A.,Wenzler, Tanja,Barszcz, Todd,Werbovetz, Karl A.,Brun, Reto,Tidwell, Richard R.
, p. 4657 - 4667 (2009)
A series of novel pyridyl analogues 1-18 of antiprotozoal drug 1,5-bis(4-amidinophenoxy)pentane (pentamidine) has been synthesized and tested for in vitro activities against Trypanosoma brucei rhodesiense, Plasmodium falciparum, and Leishmania donovani, a
Design, synthesis and in vitro activity of phidianidine B derivatives as novel PTP1B inhibitors with specific selectivity
Zhang, Li,Jiang, Cheng-Shi,Gao, Li-Xin,Gong, Jing-Xu,Wang, Zhong-Hua,Li, Jing-Ya,Li, Jia,Li, Xu-Wen,Guo, Yue-Wei
, p. 778 - 781 (2016)
A series of phidianidine B derivatives were synthesized by introducing various heterocyclic rings. Their inhibitory effects on PTP1B and other PTPs (TCPTP, SHP1, SHP2 and LAR) were evaluated. A majority of them displayed significant inhibitory potency and specific selectivity over PTP1B. The SAR and molecular docking analysis were also described.
Efficient enhancement of copper-pyridineoxazoline catalysts through immobilization and process design
Aranda,Cornejo,Fraile,Garcia-Verdugo,Gil,Luis,Mayoral,Martinez-Merino,Ochoa
supporting information; experimental part, p. 983 - 990 (2011/06/19)
Copper-pyridineoxazoline (Cu-pyox) complexes are poor homogeneous catalysts for asymmetric cyclopropanation reactions. Pyox ligands have been immobilized by polymerization of monomers possessing a vinyl group directly attached to position 6 with styrene a