127682-80-8Relevant articles and documents
Synthesis and anti-HIV activity of isonucleosides
Huryn,Sluboski,Tam,Weigele,Sim,Anderson,Mitsuya,Broder
, p. 2347 - 2354 (2007/10/02)
A series of isomeric 2',3'-dideoxynucleosides which contains a modified carbohydrate moiety has been prepared. This class of compounds was designed to mimic the activity of known anti-HIV dideoxynucleosides, while imparting enhanced chemical and enzymatic
SYNTHESYS OF ISO-DDA, MEMBER OF A NOVEL CLASS OF ANTI-HIV AGENTS
Huryn, Donna M.,Sluboski, Barbara C.,Tam, Steve Y,,Todaro, Luis J.,Weigele, Manfred
, p. 6259 - 6262 (2007/10/02)
Iso-ddA (3) represents a new class of potential anti-AIDS drugs.Synthetic approaches to this compound involving nucleophilic additions to a novel carbohydrate framework are discussed.