128256-23-5

Basic information

• Product Name: 4-{4-nitrophenyl}-6-methyl-2-phenylquinazoline
• Synonyms: 4-{4-nitrophenyl}-6-methyl-2-phenylquinazoline
• CAS NO: 128256-23-5
• Molecular Formula: C₂₁H₁₅N₃O₂
• Molecular Weight: 341.3627
• Mol File: 128256-23-5.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-{4-nitrophenyl}-6-methyl-2-phenylquinazoline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-{4-nitrophenyl}-6-methyl-2-phenylquinazoline(128256-23-5)
• EPA Substance Registry System: 4-{4-nitrophenyl}-6-methyl-2-phenylquinazoline(128256-23-5)

Safety Data

• Hazardous Substances Data: 128256-23-5(Hazardous Substances Data)

Upstream product

• 66275-61-4 N-Chloro-N'-(4-methylphenyl)benzamidine 
• 1859-00-3 (Z)-N'-(4-methylphenyl)benzamidine 
• 555-16-8 4-nitrobenzaldehdye 
• 71316-14-8 N'-(4-methylphenyl)-N-(triphenylphosphoranylidene)-benzenecarboximidamide 

Relevant articles and documents

Microwave Assisted Aza-Wittig Reactions of N-Imidoyliminophosphorane with Aldehydes: A Convenient and Selective Route to Quinazolines

A novel synthetic strategy for the selective synthesis of biologically important quinazolines with shorter reaction times, better yields, lower energy inputs and hassle free work up using a domestic microwave oven is reported.

A convenient synthesis of Quinazoline ring by tandem aza-Wittig reaction/electrocyclic ring closure

3,4-D-Dihydroquinazolines and Quinazolines were prepared starting from N'-aryl-N-(triphenylphosphoranilidene)-carboximidamides and aliphatic or aromatic aldehydes. The mechanism of the reaction is discussed.