129306-06-5

Basic information

• Product Name: (E)-5-benzyl-7-(hydroxyimino)-5-azaspiro[2.4]heptan-4-one
• Synonyms: (E)-5-benzyl-7-(hydroxyimino)-5-azaspiro[2.4]heptan-4-one;5-Azaspiro[2.4]heptane-4,7-dione, 5-(phenylmethyl)-, 7-oxime
• CAS NO: 129306-06-5
• Molecular Formula: C13H14N2O2
• Molecular Weight: 230.26246
• Mol File: 129306-06-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 490.5±45.0 °C(Predicted)
• Appearance: /
• Density: 1.34±0.1 g/cm3(Predicted)
• PKA: 11.24±0.20(Predicted)
• CAS DataBase Reference: (E)-5-benzyl-7-(hydroxyimino)-5-azaspiro[2.4]heptan-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-5-benzyl-7-(hydroxyimino)-5-azaspiro[2.4]heptan-4-one(129306-06-5)
• EPA Substance Registry System: (E)-5-benzyl-7-(hydroxyimino)-5-azaspiro[2.4]heptan-4-one(129306-06-5)

Safety Data

• Hazardous Substances Data: 129306-06-5(Hazardous Substances Data)

Usage

General Description

(E)-5-benzyl-7-(hydroxyimino)-5-azaspiro[2.4]heptan-4-one is a chemical compound with the molecular formula C14H17NO2. It is a spiro compound, meaning it contains a unique five-membered ring structure. (E)-5-benzyl-7-(hydroxyimino)-5-azaspiro[2.4]heptan-4-one has a benzyl group attached to the nitrogen atom and a hydroxyimino group attached to one of the carbon atoms in the ring. It is commonly used in organic synthesis and pharmaceutical research, where it may have potential applications due to its unique structure and properties. Additionally, it may also have potential biological activities that make it of interest for further study in medicinal chemistry and drug development.

Upstream product

• 129306-04-3 5-benzyl-5-azaspiro[2.4]heptane-4,7-dione 
• 331443-52-8 N-benzyl-1-(2-bromoacetyl)cyclopropanecarboxamide 
• 147011-39-0 1-acetyl-N-[benzyl]cyclopropane-1-carboxamide 
• 882-36-0 N-benzyl-3-oxobutanamide 

Downstream Products

• 129306-07-6 5-benzyl-5-azaspiro[2.4]heptane-7-amine 
• 129306-13-4 5-phenylmethyl-N-(tert-butoxycarbonyl)-5-azaspiro[2.4]heptane-7-amine 
• 152513-88-7 (7S)-5-aza-7-tert-butoxycarbonylaminospiro[2.4]heptan 
• 144282-35-9 5-benzyl-7(S)-amino-5-azaspiro[2,4]heptane 
• 1432056-70-6 5-benzyl-7(S)-tert-butoxycarbonylamino-5-azaspiro[2,4]heptane 

Relevant articles and documents

Substituted alkynyl pyridine compounds and methods of use thereof, and use thereof

The invention provides a substituted alkynylpyridine compound with a structure represented by a formula (I) as described in the specification and a pharmaceutically acceptable salt and a medicinal preparation thereof. The compound is used for adjusting activity of protein kinase and adjusting intercellular or intracellular signal response. The invention also relates to a pharmaceutical composition including the compound provided by the invention and a method of applying the pharmaceutical composition in treating mammals, especially in treating highly proliferative diseases of the mankind.

SUBSTITUTED ALKYNYL PYRIDINE COMPOUNDS AND METHODS OF USE

The present invention provides novel substituted alkynyl pyridine compounds, pharmaceutical acceptable salts and formulations thereof useful in modulating the protein tyrosine kinase activity, and in modulating cellular activities such as proliferation, differentiation, apoptosis, migration and invasion. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of hyperproliferative disorders in mammals, especially humans.