129974-80-7

Basic information

• Product Name: (1R)-Bicyclo<2.2.1>hept-2-yl (D)-2-chloropropanoate
• CAS NO: 129974-80-7
• Molecular Weight: 202.681
• Mol File: 129974-80-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R)-Bicyclo<2.2.1>hept-2-yl (D)-2-chloropropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (1R)-Bicyclo<2.2.1>hept-2-yl (D)-2-chloropropanoate(129974-80-7)
• EPA Substance Registry System: (1R)-Bicyclo<2.2.1>hept-2-yl (D)-2-chloropropanoate(129974-80-7)

Safety Data

• Hazardous Substances Data: 129974-80-7(Hazardous Substances Data)

Upstream product

• 129974-80-7 (RS)-Bicyclo<2.2.1>hept-2-yl (D)-2-chloropropanoate 
• 129974-80-7 (RS)-Bicyclo<2.2.1>hept-2-yl (L)-2-chloropropanoate 

Downstream Products

• 29617-66-1 (S)-2-chloropropanoic acid 
• 497-36-9 (S)-Bicyclo[2.2.1]heptan-2-ol 
• 129974-80-7 (1R)-Bicyclo<2.2.1>hept-2-yl (L)-2-chloropropanoate 
• 129974-80-7 (1R)-Bicyclo<2.2.1>hept-2-yl (D)-2-chloropropanoate 
• 7474-05-7 (R)-2-chloropropionic acid 

Relevant articles and documents

ENZYMATIC RECOGNITION OF DIASTEREOMERIC ESTERS

Aiming to improve the enantioselectivity of enzymatic resolution of esters, lipase catalyzed hydrolysis of (D)- and (L)-2-chloropropanoates of four racemic alcohols and transesterification of ethyl (DL)-2-chloropropanoate with optically pure alcohols was investigated.Thus, (rac)-endo-2-norbornyl (L)-2-chloropropanoate was hydrolized by lipase P about 5 times more selectively than its corresponding (D)-counterpart and optically pure (1R,2S,5R)-menthol was obtained by transesterification of its racemate with ethyl (D)-2-chloropropanoate using Candida cylindracea (CC)lipase.From the results obtained it seems obvious that lipases CC and P mainly can recognize the chirality of an alcohol moiety rather than that of an acid