1309434-72-7

Basic information

• Product Name: N-(3-chloro-4-(1,3-dioxo-2-azaspiro[4.5]decan-2-yl)phenyl)picolinamide
• CAS NO: 1309434-72-7
• Molecular Weight: 397.861
• Mol File: 1309434-72-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(3-chloro-4-(1,3-dioxo-2-azaspiro[4.5]decan-2-yl)phenyl)picolinamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-chloro-4-(1,3-dioxo-2-azaspiro[4.5]decan-2-yl)phenyl)picolinamide(1309434-72-7)
• EPA Substance Registry System: N-(3-chloro-4-(1,3-dioxo-2-azaspiro[4.5]decan-2-yl)phenyl)picolinamide(1309434-72-7)

Safety Data

• Hazardous Substances Data: 1309434-72-7(Hazardous Substances Data)

Upstream product

• 252019-65-1 tert-butyl N-[(tert-butoxy)carbonyl]-N-(2-chloro-4-nitrophenyl)carbamate 
• 252019-51-5 N¹,N¹-bis(tert-butoxycarbonyl)-2-chloro-p-phenylenediamine 
• 121-87-9 2-Chloro-4-nitroaniline 
• 1308656-31-6 bis(tert-butyl 2-chloro-4-(picolinamido)phenyl)carbamate 

Relevant articles and documents

Discovery, synthesis, and structure-activity relationship development of a series of N -4-(2,5-dioxopyrrolidin-1-yl)phenylpicolinamides (VU0400195, ML182): Characterization of a novel positive allosteric modulator of the metabotropic glutamate receptor 4

There is an increasing amount of literature data showing the positive effects on preclinical antiparkinsonian rodent models with selective positive allosteric modulators of metabotropic glutamate receptor 4 (mGlu4). However, most of the data ge