1312341-52-8Relevant articles and documents
Stereoselective Oxidation of Titanium(IV) Enolates with Oxygen
Gómez-Palomino, Alejandro,Romea, Pedro,Urpí, Fèlix
, p. 2721 - 2726 (2018/06/08)
A novel approach to synthesize enantiomerically pure α-hydroxy carboxylic derivatives is reported. A highly stereoselective oxidation of titanium(IV) enolates from chiral N -acyloxazolidinones is performed with oxygen under simple experimental conditions
A simple method for asymmetric trifluoromethylation of N-acyl oxazolidinones via Ru-catalyzed radical addition to zirconium enolates
Herrmann, Aaron T.,Smith, Lindsay L.,Zakarian, Armen
, p. 6976 - 6979 (2012/06/15)
A Ru-catalyzed direct thermal trifluoromethylation and perfluoroalkylation of N-acyloxazolidinones has been developed. The reaction is experimentally simple and requires inexpensive reagents while providing good yields of products with good levels of stereocontrol. Preliminary studies have shown notable compatibility with functional groups, aromatics, and certain heteroaromatic substituents. The described method provides a useful alternative for the synthesis of fluorinated materials in an experimentally convenient manner.