133125-17-4

Basic information

• Product Name: 2(S)-2-(benzyloxycarbonylamino)-4-iodobutyric acid tert-butyl ester
• Synonyms: 2(S)-2-(benzyloxycarbonylamino)-4-iodobutyric acid tert-butyl ester
• CAS NO: 133125-17-4
• Molecular Weight: 419.259
• Mol File: 133125-17-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2(S)-2-(benzyloxycarbonylamino)-4-iodobutyric acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2(S)-2-(benzyloxycarbonylamino)-4-iodobutyric acid tert-butyl ester(133125-17-4)
• EPA Substance Registry System: 2(S)-2-(benzyloxycarbonylamino)-4-iodobutyric acid tert-butyl ester(133125-17-4)

Safety Data

• Hazardous Substances Data: 133125-17-4(Hazardous Substances Data)

Upstream product

• 78266-81-6 tert-butyl N-[(benzyloxy)carbonyl]-L-homoserinate 
• 47307-26-6 (S)-2-benzyloxycarbonylamino-succinic acid 1-tert-butyl ester 
• 4125-93-3 (S)-3-amino-4-(tert-butoxy)-4-oxobutanoic acid 
• 501-53-1 benzyl chloroformate 
• 3160-47-2 N-(benzyloxycarbonyl)-L-aspartic acid 4-methyl ester 
• 60079-12-1 β-Methyl α-tert-butyl (2S)-N-(benzyloxycarbonyl)aspartate 

Downstream Products

• 133125-22-1 (2S,5S)-2-Benzyloxycarbonylamino-5-(2-methoxy-phenyl)-hexanedioic acid 1-tert-butyl ester 6-methyl ester 
• 133125-24-3 (2R,5S)-2-Benzyloxycarbonylamino-5-(2-methoxy-phenyl)-hexanedioic acid 1-tert-butyl ester 6-methyl ester 
• 1260243-84-2 tert-butyl 1-[(S)-3-benzyloxycarbonylamino-4-tert-butoxy-4-oxobutyl]-3,3-dimethyl-1,3-azasilolidine-5-carboxylate 
• 1314037-14-3 C₃₇H₆₃N₃O₁₀SSi 
• 1260243-89-7 tert-butyl (S)-1-[(S)-3-benzyloxycarbonylamino-4-tert-butoxy-4-oxobutyl]-5-oxopyrrolidine-2-carboxylate 
• 1260243-83-1 tert-butyl (S)-1-[(S)-3-benzyloxycarbonylamino-4-tert-butoxy-4-oxobutyl]pyrrolidine-2-carboxylate 
• 1235453-07-2 tert-butyl (2S,3'S)-1-(3'-benzyloxycarbonylamino-4'-tert-butoxy-4'-oxobutyl)azetidine-2-carboxylate 
• 1246617-26-4 C₄₃H₆₄N₂O₁₁S 
• 1246617-30-0 C₆₅H₉₇N₃O₁₆S₂ 
• 133125-21-0 (2S,5S)-2-Benzyloxycarbonylamino-5-phenyl-hexanedioic acid 1-tert-butyl ester 6-methyl ester 
• 133125-23-2 (2R,5S)-2-Benzyloxycarbonylamino-5-phenyl-hexanedioic acid 1-tert-butyl ester 6-methyl ester 

Relevant articles and documents

Synthesis of desmosine-containing cyclic peptide for the possible elucidation of elastin crosslinking structure

Elastin is a vital extracellular matrix protein, which is known for providing elasticity in numerous tissues. It is formed by the self-assembly and subsequent crosslinking of elastin precursor, tropoelastin. Two tetrafunctional, pyridinium-based amino acids desmosine and isodesmosine are exclusively found in elastin and play an important role as crosslinkers. Structural elucidation of elastin has eluded scientists to date, owing to the highly cross-linked structure and insoluble nature. Therefore, in this study, we aimed to synthesize a desmosine-containing cyclic peptide as a partial elastin mimic, in order to eventually facilitate the elucidation of the crosslinking pattern of elastin by mass spectrometric analysis.

The crystallographic structure of thermoNicotianamine synthase with a synthetic reaction intermediate highlights the sequential processing mechanism

We determined the three-dimensional structure of a complex between an archaeal nicotianamine synthase homologue and a chemically synthesised reaction intermediate. This structure suggests that the enzymes cavity allows both an ordered substrate binding an

PYRIMIDINE DERIVATIVES USEFUL AS DHFR INHIBITORS

Compounds of formula (I) or (II) are dihydrofolatereductase inhibitors, useful for the treatment of, for example, cell proliferative diseases: wherein A and D are independently -CHR6- or -NR6; E and G are independently =CR6/sub