1375180-06-5

Basic information

• Product Name: 3-(3,4-bis(benzyloxy)phenyl)propanoyl chloride
• Synonyms: 3-(3,4-bis(benzyloxy)phenyl)propanoyl chloride
• CAS NO: 1375180-06-5
• Molecular Weight: 380.871
• Mol File: 1375180-06-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-(3,4-bis(benzyloxy)phenyl)propanoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3,4-bis(benzyloxy)phenyl)propanoyl chloride(1375180-06-5)
• EPA Substance Registry System: 3-(3,4-bis(benzyloxy)phenyl)propanoyl chloride(1375180-06-5)

Safety Data

• Hazardous Substances Data: 1375180-06-5(Hazardous Substances Data)

Upstream product

• 93559-04-7 3-(3,4-bis-benzyloxyphenyl)-propionic acid 
• 1375180-02-1 benzyl 3-(3,4-bis(benzyloxy)phenyl)propanoate 
• 1078-61-1 dihydrocaffeic acid 
• 2107-70-2 3,4-methoxycinnamic acid 

Downstream Products

• 1375180-08-7 C₄₃H₅₃N₃O₇ 
• 1375180-09-8 benzyl 3-(3-(3,4-bis(benzyloxy)phenyl)propanamido)propyl(4-aminobutyl)carbamate 
• 1375180-11-2 C₄₁H₄₈N₄O₅ 
• 1375180-12-3 C₆₄H₆₈N₄O₈ 
• 1375180-15-6 benzyl 4-(3-(3,4-bis(benzyloxy)phenyl)-N-(3-aminopropyl)propanamido)butyl(3-(3-(3,4-bis(benzyloxy)phenyl)propanamido)propyl)carbamate 
• 1375179-78-4 kukoamine B malate 
• 1375179-80-8 kukoamine B succinate 
• 1375179-82-0 kukoamine B lactate 
• 1375179-88-6 kukoamine B glutamate 
• 1375179-93-3 kukoamine B sulfate 
• 1375179-96-6 kukoamine B maleate 
• 1375179-97-7 kukoamine B aspartate 
• 1375180-00-9 kukoamine B phosphate 

Relevant articles and documents

The Total Synthesis of Spermine Alkaloid Kukoamine Bimesylate

The first total synthesis of kukoamine B bimesylate was completed from 1,4-diaminobutane dihydrochloride in 12 steps with a 11.4% overall yield, and all the steps could be carried out at a kilogram scale. The cyano groups were used as the precursor of amino groups to avoid the competitive reaction delicately. The aza-Michael addition reaction, amidation and hydrogenation of the cyano group sequence was streamlined as a general approach towards the synthesis of polyamine structures.

SALTS OF KUKOAMINE B, PREPARATION METHOD AND USE THEREOF

Provided are salts of kukoamine B, their preparation method and their use in preventing and treating sepsis diseases.