142954-98-1

Basic information

• Product Name: (2R,3S,7R,7aS)-7-Iodomethyl-3-methyl-2-phenyl-tetrahydro-pyrrolo[2,1-b]oxazol-5-one
• Synonyms: (2R,3S,7R,7aS)-7-Iodomethyl-3-methyl-2-phenyl-tetrahydro-pyrrolo[2,1-b]oxazol-5-one
• CAS NO: 142954-98-1
• Molecular Weight: 357.191
• Mol File: 142954-98-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,3S,7R,7aS)-7-Iodomethyl-3-methyl-2-phenyl-tetrahydro-pyrrolo[2,1-b]oxazol-5-one(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3S,7R,7aS)-7-Iodomethyl-3-methyl-2-phenyl-tetrahydro-pyrrolo[2,1-b]oxazol-5-one(142954-98-1)
• EPA Substance Registry System: (2R,3S,7R,7aS)-7-Iodomethyl-3-methyl-2-phenyl-tetrahydro-pyrrolo[2,1-b]oxazol-5-one(142954-98-1)

Safety Data

• Hazardous Substances Data: 142954-98-1(Hazardous Substances Data)

Upstream product

• 137314-81-9 2-Chloro-1-((2S,4S,5R)-4-methyl-5-phenyl-2-vinyl-oxazolidin-3-yl)-ethanone 
• 16251-50-6 (1S,2R)-(+)-2-chloro-N-(2-hydroxy-1-methyl-2-phenylethyl)acetamide 
• 492-41-1 (1R,2S)-norephedrine 
• 137314-85-3 2-Iodo-1-((2S,4S,5R)-4-methyl-5-phenyl-2-vinyl-oxazolidin-3-yl)-ethanone 

Downstream Products

• 137314-90-0 (2R,3S,7R,7aS)-3,7-Dimethyl-2-phenyl-tetrahydro-pyrrolo[2,1-b]oxazol-5-one 

Relevant articles and documents

Stereoselective Radical-Mediated Cyclization of Norephedrine Derived α-Iodoamides: Synthesis of Enantiopure Pyrrolidines and Transition State Modelling

Radical-mediated cyclization of norephedrine derived α-iodoamides 1 was found to be highly stereoselective ( 97:3) favouring diastereoisomer 2.Bicyclic lactams 2 were transformed in high yields into enantiomerically pure pyrrolidines 10.Transition stat