170804-18-9

Basic information

• Product Name: ETHYL 3-AMINO-4,4,4-TRIFLUOROBUTYRATE
• Synonyms: ETHYL 3-AMINO-4,4,4-TRIFLUOROBUTYRATE;Ethyl 3-amino-4,4,4-trifluorobutyrate 95%;Ethyl3-amino-4,4,4-trifluorobutyrate95%;Ethyl 3-amino-4,4,4-trifluorobutanoate 95%;Ethyl 3-amino-4,4,4-trifluorobutanoate;Ethyl3-amino-4,4,4-trifluorobutanoate95%
• CAS NO: 170804-18-9
• Molecular Formula: C₆H₁₀F₃NO₂
• Molecular Weight: 185.14
• Mol File: 170804-18-9.mol
• Article Data: 3

Chemical Properties

• Melting Point: 100-102°C
• Boiling Point: 70-71°C 4mm
• Flash Point: 70-71°C/4mm
• Appearance: /
• Density: 1.222 g/cm³
• Vapor Pressure: 0.671mmHg at 25°C
• Refractive Index: 1.3831
• Storage Temp.: 2-8°C
• PKA: 4.72±0.50(Predicted)
• Sensitive: Air Sensitive
• BRN: 6136102
• CAS DataBase Reference: ETHYL 3-AMINO-4,4,4-TRIFLUOROBUTYRATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 3-AMINO-4,4,4-TRIFLUOROBUTYRATE(170804-18-9)
• EPA Substance Registry System: ETHYL 3-AMINO-4,4,4-TRIFLUOROBUTYRATE(170804-18-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-43
• Safety Statements: 26-36/37/39-36/37
• HazardClass: 8
• Hazardous Substances Data: 170804-18-9(Hazardous Substances Data)

Usage

General Description

Ethyl 3-amino-4,4,4-trifluorobutyrate is a specialty chemical compound. It is also known by its CAS number, 66424-58-8. This organic compound features an ethyl group, an amino group, and a trifluorobutyrate group in its structure. Its unique chemical configuration allows it to serve various specific functions in many chemical reactions. Due to the presence of the trifluorobutyrate and amino group, it also exhibits certain distinguishing characteristics such as its fluorination, featuring three fluorine atoms. As it is a specialized chemical, its use is often defined by the requirements of specific chemical reactions or processes.

InChI:InChI=1/C6H10F3NO2/c1-2-12-5(11)3-4(10)6(7,8)9/h4H,2-3,10H2,1H3

Upstream product

• 372-31-6 ethyl 4,4,4-trifluoroacetoacetate 
• 79424-03-6 ethyl 4,4,4-trifluoro-2-butynate 
• 170804-10-1 3-benzylamino-4,4,4-trifluorobut-2-enoic acid ethyl ester 

Downstream Products

• 882423-18-9 ethyl 4,4,4-trifluoro-3-(3-(trifluoromethyl)phenylsulfonamido)butanoate 
• 914223-46-4 3-amino-4,4,4-trifluorobutan-1-ol 

Relevant articles and documents

BICYCLOHEPTANE PYRROLIDINE OREXIN RECEPTOR AGONISTS

The present invention is directed to bicyclo[4.1.0]heptane pyrrolidine compounds which are agonists of orexin receptors. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which orexin receptors are involved.

A convenient synthesis of perfluoroalkylated enamines and vinyl phosphonates

The reaction of fluoroalkynes with ammonia and benzylamine gave perfluoroalkylated enamines predominantly as the Z isomer, which were hydrogenated with palladium on carbon to afford perfluoroalkylated β-amino acids in good yield.The reaction of fluoroalky