174543-80-7 Usage
General Description
The chemical compound "(3R)-Amino-3-methyl-piperidine-1-carboxylic acid benzyl ester" is a specific type of amino acid derivative. It consists of a piperidine ring with an amino group and a methyl group attached to it, as well as a carboxylic acid group and a benzyl ester group. (3R)-Amino-3-methyl-piperidine-1-carboxylic acid benzyl ester is commonly used in the pharmaceutical industry, particularly in the synthesis of various drugs and biologically active molecules. Its unique structure and properties make it useful for creating new pharmaceutical compounds with potential therapeutic applications. Additionally, its benzyl ester group makes it a suitable intermediate for the synthesis of other complex organic molecules. Overall, "(3R)-Amino-3-methyl-piperidine-1-carboxylic acid benzyl ester" is an important compound with potential applications in drug development and organic synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 174543-80-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,4,5,4 and 3 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 174543-80:
(8*1)+(7*7)+(6*4)+(5*5)+(4*4)+(3*3)+(2*8)+(1*0)=147
147 % 10 = 7
So 174543-80-7 is a valid CAS Registry Number.
174543-80-7Relevant articles and documents
On the Ritter reaction of cyclic hydroxyamines: Synthesis of conformationally-restricted reduced amide dipeptide isosteres
Taylor, G. Mark,Baker, Stewart J.,Gedney, Andrea,Pearson, David J.,Sibley, Graham E. M.
, p. 1297 - 1300 (2007/10/03)
The Ritter reactions of 3-alkyl-3-hydroxyazetidine or -piperidine derivatives give low yields of the desired products, whereas the 3-alkyl-3-hydroxy-pyrrolidine and 4-alkyl-4-hydroxy-piperidine derivatives react smoothly to give the corresponding acetamides. An alternative route to 3-acylamino-3-alkylpiperidines, which were designed as conformationally-restricted reduced amide dipeptide isosteres, was devised from nipecotic acid vai a Hofmann rearrangement.
