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179246-11-8

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179246-11-8 Usage

General Description

6-Acetoxy-4-chloroquinazoline is a chemical compound with the molecular formula C10H8ClNO2. It is a chlorinated quinazoline derivative that contains an acetoxy group. 6-ACETOXY-4-CHLOROQUINAZOLINE is commonly used in the pharmaceutical industry for its potential medicinal properties. It has been studied for its anti-cancer, anti-inflammatory, and antimicrobial activities, with potential applications in drug development. The presence of both a chloro and acetoxy group in its structure suggests that 6-acetoxy-4-chloroquinazoline may have a wide range of biological activities, making it a promising candidate for further research and development in the field of medicinal chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 179246-11-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,9,2,4 and 6 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 179246-11:
(8*1)+(7*7)+(6*9)+(5*2)+(4*4)+(3*6)+(2*1)+(1*1)=158
158 % 10 = 8
So 179246-11-8 is a valid CAS Registry Number.

179246-11-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name (4-chloroquinazolin-6-yl) acetate

1.2 Other means of identification

Product number -
Other names 4-chloro-6-acetate-quinazoline

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:179246-11-8 SDS

179246-11-8Relevant articles and documents

HER2 Kinase-Targeted Breast Cancer Therapy: Design, Synthesis, and in Vitro and in Vivo Evaluation of Novel Lapatinib Congeners as Selective and Potent HER2 Inhibitors with Favorable Metabolic Stability

Elwaie, Tamer A.,Abbas, Safinaz E.,Aly, Enayat I.,George, Riham F.,Ali, Hamdy,Kraiouchkine, Nikolai,Abdelwahed, Khaldoun S.,Fandy, Tamer E.,El Sayed, Khalid A.,Abd Elmageed, Zakaria Y.,Ali, Hamed I.

, p. 15906 - 15945 (2021/01/09)

HER2 kinase as a well-established target for breast cancer (BC) therapy is associated with aggressive clinical outcomes; thus, herein we present structural optimization for HER2-selective targeting. HER2 profiling of the developed derivatives demonstrated

Hetero-aromatic compound and its use in medicine

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Paragraph 1632; 1635-1636, (2019/07/04)

The invention provides a hetero-aromatic compound or a stereisomer, geometric isomer, tautomer, despinner, nitrogen oxide, hydrate, solvate, metabolite, metabolism precursor and pharmaceutically acceptable salt or prodrug thereof, which is used for treating proliferative diseases. The invention also discloses a pharmaceutical composition containing the compound and an application of the compound or pharmaceutical composition thereof in preparation of a medicine for treating proliferative diseases.

Kuikui zuo lin kind of target anti- tumor compound and its preparation method and application (by machine translation)

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, (2017/08/31)

The present invention provides a chemical formula (I) indicated by the kuikui zuo lin kind of target anti- tumor compound and its preparation method, in particular to EGFR, HER - 2 and DNA multi-target anti- tumor compounds, also provides a method for preparing the same and in the application of the anti-tumor medicament. Studies show that the compounds of the invention have significant anti-tumor activity, metabolic stability relative to the reference substance EMB - 3 is improved notably. (by machine translation)

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